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Cerebrospinal fluid levels of the synaptic protein neurogranin correlates with cognitive decline in prodromal Alzheimer's disease.

Kvartsberg, Hlin; Duits, Flora H; Ingelsson, Martin; Andreasen, Niels; Öhrfelt, Annika; Andersson, Kerstin; Brinkmalm, Gunnar; Lannfelt, Lars; Minthon, Lennart LU and Hansson, Oskar LU , et al. (2015) In Alzheimer's & Dementia 11(10). p.1180-1190
Abstract
Synaptic dysfunction is an early event in Alzheimer's disease (AD) pathogenesis and directly related to cognitive impairment. Consequently, synaptic biomarkers may be valuable tools for both early diagnosis and disease stage. Neurogranin (Ng) is a postsynaptic protein involved in memory consolidation.
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Contribution to journal
publication status
published
subject
in
Alzheimer's & Dementia
volume
11
issue
10
pages
1180 - 1190
publisher
Elsevier
external identifiers
  • pmid:25533203
  • wos:000363968000007
  • scopus:84945471565
ISSN
1552-5279
DOI
10.1016/j.jalz.2014.10.009
language
English
LU publication?
yes
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760272cc-7fa1-46d4-9acf-1fcd6dfb0920 (old id 4905754)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/25533203?dopt=Abstract
date added to LUP
2015-01-07 14:09:27
date last changed
2017-11-05 03:11:37
@article{760272cc-7fa1-46d4-9acf-1fcd6dfb0920,
  abstract     = {Synaptic dysfunction is an early event in Alzheimer's disease (AD) pathogenesis and directly related to cognitive impairment. Consequently, synaptic biomarkers may be valuable tools for both early diagnosis and disease stage. Neurogranin (Ng) is a postsynaptic protein involved in memory consolidation.},
  author       = {Kvartsberg, Hlin and Duits, Flora H and Ingelsson, Martin and Andreasen, Niels and Öhrfelt, Annika and Andersson, Kerstin and Brinkmalm, Gunnar and Lannfelt, Lars and Minthon, Lennart and Hansson, Oskar and Andreasson, Ulf and Teunissen, Charlotte E and Scheltens, Philip and Van der Flier, Wiesje M and Zetterberg, Henrik and Portelius, Erik and Blennow, Kaj},
  issn         = {1552-5279},
  language     = {eng},
  number       = {10},
  pages        = {1180--1190},
  publisher    = {Elsevier},
  series       = {Alzheimer's & Dementia},
  title        = {Cerebrospinal fluid levels of the synaptic protein neurogranin correlates with cognitive decline in prodromal Alzheimer's disease.},
  url          = {http://dx.doi.org/10.1016/j.jalz.2014.10.009},
  volume       = {11},
  year         = {2015},
}