Primary mesenchymal stem cells in human transplanted lungs are CD90/CD105 perivascularly located tissue-resident cells.
(2014) In BMJ Open Respiratory Research 1(1).- Abstract
- Mesenchymal stem cells (MSC) have not only been implicated in the development of lung diseases, but they have also been proposed as a future cell-based therapy for lung diseases. However, the cellular identity of the primary MSC in human lung tissues has not yet been reported. This study therefore aimed to identify and characterise the 'bona fide' MSC in human lungs and to investigate if the MSC numbers correlate with the development of bronchiolitis obliterans syndrome in lung-transplanted patients.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/4912571
- author
- organization
-
- Lung Biology (research group)
- Respiratory Medicine, Allergology, and Palliative Medicine
- Stem Cell Center
- Division of Clinical Genetics
- BioCARE: Biomarkers in Cancer Medicine improving Health Care, Education and Innovation
- Department of Health Sciences
- StemTherapy: National Initiative on Stem Cells for Regenerative Therapy
- EpiHealth: Epidemiology for Health
- publishing date
- 2014
- type
- Contribution to journal
- publication status
- published
- subject
- in
- BMJ Open Respiratory Research
- volume
- 1
- issue
- 1
- article number
- e000027
- publisher
- BMJ Publishing Group
- external identifiers
-
- pmid:25478178
- pmid:25478178
- scopus:85006673989
- ISSN
- 2052-4439
- DOI
- 10.1136/bmjresp-2014-000027
- language
- English
- LU publication?
- yes
- additional info
- The information about affiliations in this record was updated in December 2015. The record was previously connected to the following departments: Lung Biology (013212002), Division of Clinical Genetics (013022003), Respiratory Medicine and Allergology (013230111), Stem Cell Center (013041110), Caring Sciences (Closed 2012) (016514020)
- id
- 9842c6ec-96e6-4f26-8820-ea02ffc4fd0b (old id 4912571)
- alternative location
- http://www.ncbi.nlm.nih.gov/pubmed/25478178?dopt=Abstract
- date added to LUP
- 2016-04-01 15:05:13
- date last changed
- 2024-02-25 22:33:12
@article{9842c6ec-96e6-4f26-8820-ea02ffc4fd0b, abstract = {{Mesenchymal stem cells (MSC) have not only been implicated in the development of lung diseases, but they have also been proposed as a future cell-based therapy for lung diseases. However, the cellular identity of the primary MSC in human lung tissues has not yet been reported. This study therefore aimed to identify and characterise the 'bona fide' MSC in human lungs and to investigate if the MSC numbers correlate with the development of bronchiolitis obliterans syndrome in lung-transplanted patients.}}, author = {{Rolandsson Enes, Sara and Andersson Sjöland, Annika and Brune, Jan Claas and Li, Hongzhe and Kassem, Moustapha and Mertens, Fredrik and Westergren, Albert and Eriksson, Leif and Hansson, Lennart and Skog, Ingrid and Bjermer, Leif and Scheding, Stefan and Westergren-Thorsson, Gunilla}}, issn = {{2052-4439}}, language = {{eng}}, number = {{1}}, publisher = {{BMJ Publishing Group}}, series = {{BMJ Open Respiratory Research}}, title = {{Primary mesenchymal stem cells in human transplanted lungs are CD90/CD105 perivascularly located tissue-resident cells.}}, url = {{https://lup.lub.lu.se/search/files/4331160/7696743.pdf}}, doi = {{10.1136/bmjresp-2014-000027}}, volume = {{1}}, year = {{2014}}, }