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Primary mesenchymal stem cells in human transplanted lungs are CD90/CD105 perivascularly located tissue-resident cells.

Rolandsson Enes, Sara LU ; Andersson Sjöland, Annika LU ; Brune, Jan Claas LU ; Li, Hongzhe LU ; Kassem, Moustapha ; Mertens, Fredrik LU ; Westergren, Albert LU ; Eriksson, Leif LU ; Hansson, Lennart LU and Skog, Ingrid LU , et al. (2014) In BMJ Open Respiratory Research 1(1).
Abstract
Mesenchymal stem cells (MSC) have not only been implicated in the development of lung diseases, but they have also been proposed as a future cell-based therapy for lung diseases. However, the cellular identity of the primary MSC in human lung tissues has not yet been reported. This study therefore aimed to identify and characterise the 'bona fide' MSC in human lungs and to investigate if the MSC numbers correlate with the development of bronchiolitis obliterans syndrome in lung-transplanted patients.
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organization
publishing date
type
Contribution to journal
publication status
published
subject
in
BMJ Open Respiratory Research
volume
1
issue
1
article number
e000027
publisher
BMJ Publishing Group
external identifiers
  • pmid:25478178
  • pmid:25478178
  • scopus:85006673989
ISSN
2052-4439
DOI
10.1136/bmjresp-2014-000027
language
English
LU publication?
yes
additional info
The information about affiliations in this record was updated in December 2015. The record was previously connected to the following departments: Lung Biology (013212002), Division of Clinical Genetics (013022003), Respiratory Medicine and Allergology (013230111), Stem Cell Center (013041110), Caring Sciences (Closed 2012) (016514020)
id
9842c6ec-96e6-4f26-8820-ea02ffc4fd0b (old id 4912571)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/25478178?dopt=Abstract
date added to LUP
2016-04-01 15:05:13
date last changed
2021-09-15 04:07:26
@article{9842c6ec-96e6-4f26-8820-ea02ffc4fd0b,
  abstract     = {Mesenchymal stem cells (MSC) have not only been implicated in the development of lung diseases, but they have also been proposed as a future cell-based therapy for lung diseases. However, the cellular identity of the primary MSC in human lung tissues has not yet been reported. This study therefore aimed to identify and characterise the 'bona fide' MSC in human lungs and to investigate if the MSC numbers correlate with the development of bronchiolitis obliterans syndrome in lung-transplanted patients.},
  author       = {Rolandsson Enes, Sara and Andersson Sjöland, Annika and Brune, Jan Claas and Li, Hongzhe and Kassem, Moustapha and Mertens, Fredrik and Westergren, Albert and Eriksson, Leif and Hansson, Lennart and Skog, Ingrid and Bjermer, Leif and Scheding, Stefan and Westergren-Thorsson, Gunilla},
  issn         = {2052-4439},
  language     = {eng},
  number       = {1},
  publisher    = {BMJ Publishing Group},
  series       = {BMJ Open Respiratory Research},
  title        = {Primary mesenchymal stem cells in human transplanted lungs are CD90/CD105 perivascularly located tissue-resident cells.},
  url          = {https://lup.lub.lu.se/search/files/4331160/7696743.pdf},
  doi          = {10.1136/bmjresp-2014-000027},
  volume       = {1},
  year         = {2014},
}