Sensitivity of mongolian gerbils to trichloroethylene exposure during neonatal growth
Kjellstrand, Per ; Månsson, Lennart ; Bjerkemo, M ; Lanke, Jan LU ; Holmquist, Björn LU
and Zetterqvist, Lena
LU
(1982)
In Toxicology Letters
14(1-2).
p.97-101
- Abstract
- Continuous exposure of young mongolian gerbils to trichloroethylene (230 ppm) was started at different times during the first month of life. The onset of exposure was accompanied by an increased number of deaths among the pups and by an immediate reduction in growth rate. The proportion of dead pups was greatest when exposure was started at birth, and decreased rapidly with increasing age at onset of exposure. Growth rate was partially restored approx. 1 week after the onset of exposure. After weaning the effect of the exposure on growth decreased, and the variation in the effect among different litters was considerably reduced. The enhanced sensitivity of the pups to trichloroethylene (TCE) exposure is believed to be due to a disturbance... (More)
- Continuous exposure of young mongolian gerbils to trichloroethylene (230 ppm) was started at different times during the first month of life. The onset of exposure was accompanied by an increased number of deaths among the pups and by an immediate reduction in growth rate. The proportion of dead pups was greatest when exposure was started at birth, and decreased rapidly with increasing age at onset of exposure. Growth rate was partially restored approx. 1 week after the onset of exposure. After weaning the effect of the exposure on growth decreased, and the variation in the effect among different litters was considerably reduced. The enhanced sensitivity of the pups to trichloroethylene (TCE) exposure is believed to be due to a disturbance in the mother-offspring relationship. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/4934726
- author
- Kjellstrand, Per
; Månsson, Lennart
; Bjerkemo, M
; Lanke, Jan
LU
; Holmquist, Björn
LU
and Zetterqvist, Lena
LU
- organization
- publishing date
- 1982
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- Mongolian gerbil, trichloroethylene, Meriones unguiculatus, neonatal, growth
- in
- Toxicology Letters
- volume
- 14
- issue
- 1-2
- pages
- 97 - 101
- publisher
- Elsevier
- external identifiers
-
- scopus:0020422239
- ISSN
- 1879-3169
- DOI
- 10.1016/0378-4274(82)90015-7
- language
- English
- LU publication?
- yes
- id
- cc7d58a0-e51d-4663-b517-a4ab45c88ab2 (old id 4934726)
- date added to LUP
- 2016-04-04 11:46:38
- date last changed
- 2021-01-03 08:08:15
@article{cc7d58a0-e51d-4663-b517-a4ab45c88ab2,
abstract = {{Continuous exposure of young mongolian gerbils to trichloroethylene (230 ppm) was started at different times during the first month of life. The onset of exposure was accompanied by an increased number of deaths among the pups and by an immediate reduction in growth rate. The proportion of dead pups was greatest when exposure was started at birth, and decreased rapidly with increasing age at onset of exposure. Growth rate was partially restored approx. 1 week after the onset of exposure. After weaning the effect of the exposure on growth decreased, and the variation in the effect among different litters was considerably reduced. The enhanced sensitivity of the pups to trichloroethylene (TCE) exposure is believed to be due to a disturbance in the mother-offspring relationship.}},
author = {{Kjellstrand, Per and Månsson, Lennart and Bjerkemo, M and Lanke, Jan and Holmquist, Björn and Zetterqvist, Lena}},
issn = {{1879-3169}},
keywords = {{Mongolian gerbil; trichloroethylene; Meriones unguiculatus; neonatal; growth}},
language = {{eng}},
number = {{1-2}},
pages = {{97--101}},
publisher = {{Elsevier}},
series = {{Toxicology Letters}},
title = {{Sensitivity of mongolian gerbils to trichloroethylene exposure during neonatal growth}},
url = {{http://dx.doi.org/10.1016/0378-4274(82)90015-7}},
doi = {{10.1016/0378-4274(82)90015-7}},
volume = {{14}},
year = {{1982}},
}