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Postural Orthostatic Tachycardia Syndrome (POTS) : A critical assessment

Olshansky, Brian ; Cannom, David ; Fedorowski, Artur LU orcid ; Stewart, Julian ; Gibbons, Christopher ; Sutton, Richard ; Shen, Win-Kuang ; Muldowney, James ; Chung, Tae Hwan and Feigofsky, Suzy , et al. (2020) In Progress in cardiovascular diseases 63(3). p.263-270
Abstract

Although diagnostic criteria have been developed characterizing postural orthostatic tachycardia syndrome (POTS), no single set of criteria is universally accepted. Furthermore, there are gaps in the present criteria to identify individuals who have this condition. The reproducibility of the physiological findings, the relationship of symptoms to physiological findings, the presence of symptoms alone without any physiological findings and the response to various interventions confuse rather than clarify this condition. As many disease entities can be confused with POTS, it becomes critical to identify what this syndrome is. What appears to be POTS may be an underlying condition that requires specific therapy. POTS is not simply... (More)

Although diagnostic criteria have been developed characterizing postural orthostatic tachycardia syndrome (POTS), no single set of criteria is universally accepted. Furthermore, there are gaps in the present criteria to identify individuals who have this condition. The reproducibility of the physiological findings, the relationship of symptoms to physiological findings, the presence of symptoms alone without any physiological findings and the response to various interventions confuse rather than clarify this condition. As many disease entities can be confused with POTS, it becomes critical to identify what this syndrome is. What appears to be POTS may be an underlying condition that requires specific therapy. POTS is not simply orthostatic intolerance and symptoms or intermittent orthostatic tachycardia but the syndrome needs to be characterized over time and with reproducibility. Here we address critical issues regarding the pathophysiology and diagnosis of POTS in an attempt to arrive at a rational approach to categorize the syndrome with the hope that it may help both better identify individuals and better understand approaches to therapy.

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publishing date
type
Contribution to journal
publication status
published
subject
in
Progress in cardiovascular diseases
volume
63
issue
3
pages
263 - 270
publisher
W.B. Saunders
external identifiers
  • pmid:32222376
  • scopus:85083878596
ISSN
0033-0620
DOI
10.1016/j.pcad.2020.03.010
language
English
LU publication?
no
additional info
Copyright © 2018. Published by Elsevier Inc.
id
493d6d7d-ec78-412a-bc44-12e28b102ac8
date added to LUP
2020-04-07 08:18:25
date last changed
2025-03-07 18:10:23
@article{493d6d7d-ec78-412a-bc44-12e28b102ac8,
  abstract     = {{<p>Although diagnostic criteria have been developed characterizing postural orthostatic tachycardia syndrome (POTS), no single set of criteria is universally accepted. Furthermore, there are gaps in the present criteria to identify individuals who have this condition. The reproducibility of the physiological findings, the relationship of symptoms to physiological findings, the presence of symptoms alone without any physiological findings and the response to various interventions confuse rather than clarify this condition. As many disease entities can be confused with POTS, it becomes critical to identify what this syndrome is. What appears to be POTS may be an underlying condition that requires specific therapy. POTS is not simply orthostatic intolerance and symptoms or intermittent orthostatic tachycardia but the syndrome needs to be characterized over time and with reproducibility. Here we address critical issues regarding the pathophysiology and diagnosis of POTS in an attempt to arrive at a rational approach to categorize the syndrome with the hope that it may help both better identify individuals and better understand approaches to therapy.</p>}},
  author       = {{Olshansky, Brian and Cannom, David and Fedorowski, Artur and Stewart, Julian and Gibbons, Christopher and Sutton, Richard and Shen, Win-Kuang and Muldowney, James and Chung, Tae Hwan and Feigofsky, Suzy and Nayak, Hemal and Calkins, Hugh and Benditt, David G}},
  issn         = {{0033-0620}},
  language     = {{eng}},
  month        = {{03}},
  number       = {{3}},
  pages        = {{263--270}},
  publisher    = {{W.B. Saunders}},
  series       = {{Progress in cardiovascular diseases}},
  title        = {{Postural Orthostatic Tachycardia Syndrome (POTS) : A critical assessment}},
  url          = {{http://dx.doi.org/10.1016/j.pcad.2020.03.010}},
  doi          = {{10.1016/j.pcad.2020.03.010}},
  volume       = {{63}},
  year         = {{2020}},
}