Uterine artery Doppler in high-risk pregnancies at 23-24 gestational weeks is of value in predicting adverse outcome of pregnancy and selecting cases for more intense surveillance
(2014) In Acta Obstetricia et Gynecologica Scandinavica 93(12). p.1276-1281- Abstract
- ObjectiveTo assess the role of the placental arterial Doppler examination at 23-24 gestational weeks for predicting adverse perinatal outcome in high-risk pregnancies. DesignRetrospective register study. SettingSkane University Hospital in Malmo. PopulationSix hundred and forty-five women with high-risk pregnancies, without fetal malformations or chromosomal abnormalities. MethodsPlacental (uterine and umbilical artery) Doppler ultrasound examination at 23-24 gestational weeks. Main outcome measuresAdverse perinatal outcomes including preeclampsia, small-for-gestational age newborns (smaller than 3rd percentile or smaller than the 10th percentile), preterm delivery (<34weeks or <37weeks of gestation at delivery), cesarean section,... (More)
- ObjectiveTo assess the role of the placental arterial Doppler examination at 23-24 gestational weeks for predicting adverse perinatal outcome in high-risk pregnancies. DesignRetrospective register study. SettingSkane University Hospital in Malmo. PopulationSix hundred and forty-five women with high-risk pregnancies, without fetal malformations or chromosomal abnormalities. MethodsPlacental (uterine and umbilical artery) Doppler ultrasound examination at 23-24 gestational weeks. Main outcome measuresAdverse perinatal outcomes including preeclampsia, small-for-gestational age newborns (smaller than 3rd percentile or smaller than the 10th percentile), preterm delivery (<34weeks or <37weeks of gestation at delivery), cesarean section, admission to the neonatal intensive care unit and intra-uterine fetal death. ResultsAbnormal uterine artery Doppler values were detected in 45% of this high-risk group but abnormal umbilical artery Doppler indices were only seen in 3.7%. Adverse perinatal outcome increased significantly with increasing placental vascular impedance (p<0.0001). There were seven cases of intrauterine fetal death and in five the uterine artery Doppler values at 23-24weeks were abnormal. A strong correlation between abnormal uterine artery Doppler and preeclampsia was present, but not with other forms of hypertensive disorder. ConclusionPlacental Doppler screening at 23-24weeks can be used in detecting pregnancies at risk of adverse outcome and in selecting cases for more intense surveillance. A surveillance plan is proposed based on Doppler screening at 23-24weeks of gestation. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/4982790
- author
- Li, Na ; Ghosh, Gisela LU and Gudmundsson, Saemundur LU
- organization
- publishing date
- 2014
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- Doppler, ultrasound, pregnancy, placenta, uterine artery, umbilical, artery, preeclampsia, intra-uterine growth restriction, perinatal, outcome
- in
- Acta Obstetricia et Gynecologica Scandinavica
- volume
- 93
- issue
- 12
- pages
- 1276 - 1281
- publisher
- Wiley-Blackwell
- external identifiers
-
- wos:000344876200009
- scopus:84912043452
- pmid:25155650
- ISSN
- 1600-0412
- DOI
- 10.1111/aogs.12488
- language
- English
- LU publication?
- yes
- additional info
- The information about affiliations in this record was updated in December 2015. The record was previously connected to the following departments: Obstetric, Gynaecological and Prenatal Ultrasound Research Unit (013242720), Pediatrics/Urology/Gynecology/Endocrinology (013240400)
- id
- 7eba7430-5fe1-4668-ac16-467543eb315a (old id 4982790)
- date added to LUP
- 2016-04-01 13:16:13
- date last changed
- 2022-04-21 20:40:58
@article{7eba7430-5fe1-4668-ac16-467543eb315a,
abstract = {{ObjectiveTo assess the role of the placental arterial Doppler examination at 23-24 gestational weeks for predicting adverse perinatal outcome in high-risk pregnancies. DesignRetrospective register study. SettingSkane University Hospital in Malmo. PopulationSix hundred and forty-five women with high-risk pregnancies, without fetal malformations or chromosomal abnormalities. MethodsPlacental (uterine and umbilical artery) Doppler ultrasound examination at 23-24 gestational weeks. Main outcome measuresAdverse perinatal outcomes including preeclampsia, small-for-gestational age newborns (smaller than 3rd percentile or smaller than the 10th percentile), preterm delivery (<34weeks or <37weeks of gestation at delivery), cesarean section, admission to the neonatal intensive care unit and intra-uterine fetal death. ResultsAbnormal uterine artery Doppler values were detected in 45% of this high-risk group but abnormal umbilical artery Doppler indices were only seen in 3.7%. Adverse perinatal outcome increased significantly with increasing placental vascular impedance (p<0.0001). There were seven cases of intrauterine fetal death and in five the uterine artery Doppler values at 23-24weeks were abnormal. A strong correlation between abnormal uterine artery Doppler and preeclampsia was present, but not with other forms of hypertensive disorder. ConclusionPlacental Doppler screening at 23-24weeks can be used in detecting pregnancies at risk of adverse outcome and in selecting cases for more intense surveillance. A surveillance plan is proposed based on Doppler screening at 23-24weeks of gestation.}},
author = {{Li, Na and Ghosh, Gisela and Gudmundsson, Saemundur}},
issn = {{1600-0412}},
keywords = {{Doppler; ultrasound; pregnancy; placenta; uterine artery; umbilical; artery; preeclampsia; intra-uterine growth restriction; perinatal; outcome}},
language = {{eng}},
number = {{12}},
pages = {{1276--1281}},
publisher = {{Wiley-Blackwell}},
series = {{Acta Obstetricia et Gynecologica Scandinavica}},
title = {{Uterine artery Doppler in high-risk pregnancies at 23-24 gestational weeks is of value in predicting adverse outcome of pregnancy and selecting cases for more intense surveillance}},
url = {{http://dx.doi.org/10.1111/aogs.12488}},
doi = {{10.1111/aogs.12488}},
volume = {{93}},
year = {{2014}},
}