Translocation-related sarcomas.
(2009) In Seminars in Oncology 36(4). p.312-323- Abstract
- Sarcomas with chromosomal translocations represent only about one fourth of sarcoma diagnoses. However, like gastrointestinal stromal tumor (GIST), with its characteristic KIT or PDGFRA mutations, they are particularly interesting since they provide specific biological insights and mechanisms of action that may have an impact upon prognosis or therapy. These are mechanisms we are just beginning to exploit. In this section we will review the biology and clinical impact of translocation-associated sarcomas and review the clinical findings that have made a recent impact upon patients with these diverse diagnoses.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/1469899
- author
- Mertens, Fredrik LU ; Antonescu, Cristina R ; Hohenberger, Peter ; Ladanyi, Marc ; Modena, Piergiorgio ; D'Incalci, Maurizio ; Casali, Paolo G ; Aglietta, Massimo and Alvegård, Thor LU
- organization
- publishing date
- 2009
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Seminars in Oncology
- volume
- 36
- issue
- 4
- pages
- 312 - 323
- publisher
- W.B. Saunders
- external identifiers
-
- wos:000268899600004
- pmid:19664492
- scopus:67949088340
- ISSN
- 0093-7754
- DOI
- 10.1053/j.seminoncol.2009.06.004
- language
- English
- LU publication?
- yes
- id
- 4a35f13f-db3d-45bc-aa09-64b1aee8a95e (old id 1469899)
- alternative location
- http://www.ncbi.nlm.nih.gov/pubmed/19664492?dopt=Abstract
- date added to LUP
- 2016-04-04 09:10:17
- date last changed
- 2022-03-15 17:59:19
@article{4a35f13f-db3d-45bc-aa09-64b1aee8a95e, abstract = {{Sarcomas with chromosomal translocations represent only about one fourth of sarcoma diagnoses. However, like gastrointestinal stromal tumor (GIST), with its characteristic KIT or PDGFRA mutations, they are particularly interesting since they provide specific biological insights and mechanisms of action that may have an impact upon prognosis or therapy. These are mechanisms we are just beginning to exploit. In this section we will review the biology and clinical impact of translocation-associated sarcomas and review the clinical findings that have made a recent impact upon patients with these diverse diagnoses.}}, author = {{Mertens, Fredrik and Antonescu, Cristina R and Hohenberger, Peter and Ladanyi, Marc and Modena, Piergiorgio and D'Incalci, Maurizio and Casali, Paolo G and Aglietta, Massimo and Alvegård, Thor}}, issn = {{0093-7754}}, language = {{eng}}, number = {{4}}, pages = {{312--323}}, publisher = {{W.B. Saunders}}, series = {{Seminars in Oncology}}, title = {{Translocation-related sarcomas.}}, url = {{http://dx.doi.org/10.1053/j.seminoncol.2009.06.004}}, doi = {{10.1053/j.seminoncol.2009.06.004}}, volume = {{36}}, year = {{2009}}, }