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La citologia esfoliativa congiuntivale nella sindrome di Sjögren

Sallì, L ; Damiani, S ; Jacò, V ; Compagno, M LU and Pappalardo, A (1996) In La Clinical terapeutica 147(10). p.93-489
Abstract

The study has been performed in order to give a contribution to the knowledge of the conjunctival cytology in Sjögren's syndrome. Exfoliated cells were obtained by a tampon from the inferior conjunctival sac of 11 patients affected by primary or secondary Sjögren's syndrome; the material was placed onto a microscope slide and it was stained with May-Grumwald-Giemsa, after the ferning test had been performed. Tear production had been previously assessed in all patients by Schirmer's I test and basic secretion test that showed an evident tear fluid hyposecretion. Cytoanalysis of tear fluid showed, in all patients, a marked lymphocytosis, presence of epithelial cells (sometimes cell-adhesion) and a number of "snake-cells", with a... (More)

The study has been performed in order to give a contribution to the knowledge of the conjunctival cytology in Sjögren's syndrome. Exfoliated cells were obtained by a tampon from the inferior conjunctival sac of 11 patients affected by primary or secondary Sjögren's syndrome; the material was placed onto a microscope slide and it was stained with May-Grumwald-Giemsa, after the ferning test had been performed. Tear production had been previously assessed in all patients by Schirmer's I test and basic secretion test that showed an evident tear fluid hyposecretion. Cytoanalysis of tear fluid showed, in all patients, a marked lymphocytosis, presence of epithelial cells (sometimes cell-adhesion) and a number of "snake-cells", with a nucleus-cytoplasm ratio in favour of cytoplasm. Some of those cells have a thicker cytoplasmic membrane and/or a spindle-shaped peripheral nucleus, characteristic finding of keratoconjunctivitis sicca. In all cases we found mucus and fibrin (sometimes with included cells), organic debris and big crystals, some of which aggregated.

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author
; ; ; and
alternative title
Exfoliative conjunctival cytology in Sjögren's syndrome
publishing date
type
Contribution to journal
publication status
published
keywords
Aged, Conjunctiva/metabolism, Female, Humans, Keratoconjunctivitis Sicca/pathology, Male, Middle Aged, Sjogren's Syndrome/pathology, Tears/cytology
in
La Clinical terapeutica
volume
147
issue
10
pages
93 - 489
publisher
Societa Editrice Universo
external identifiers
  • scopus:0030253039
  • pmid:9264901
ISSN
0009-9074
language
Italian
LU publication?
no
id
4b779ff4-af56-4163-b33c-20da953dfb39
date added to LUP
2020-07-17 09:42:29
date last changed
2024-01-02 14:58:11
@article{4b779ff4-af56-4163-b33c-20da953dfb39,
  abstract     = {{<p>The study has been performed in order to give a contribution to the knowledge of the conjunctival cytology in Sjögren's syndrome. Exfoliated cells were obtained by a tampon from the inferior conjunctival sac of 11 patients affected by primary or secondary Sjögren's syndrome; the material was placed onto a microscope slide and it was stained with May-Grumwald-Giemsa, after the ferning test had been performed. Tear production had been previously assessed in all patients by Schirmer's I test and basic secretion test that showed an evident tear fluid hyposecretion. Cytoanalysis of tear fluid showed, in all patients, a marked lymphocytosis, presence of epithelial cells (sometimes cell-adhesion) and a number of "snake-cells", with a nucleus-cytoplasm ratio in favour of cytoplasm. Some of those cells have a thicker cytoplasmic membrane and/or a spindle-shaped peripheral nucleus, characteristic finding of keratoconjunctivitis sicca. In all cases we found mucus and fibrin (sometimes with included cells), organic debris and big crystals, some of which aggregated.</p>}},
  author       = {{Sallì, L and Damiani, S and Jacò, V and Compagno, M and Pappalardo, A}},
  issn         = {{0009-9074}},
  keywords     = {{Aged; Conjunctiva/metabolism; Female; Humans; Keratoconjunctivitis Sicca/pathology; Male; Middle Aged; Sjogren's Syndrome/pathology; Tears/cytology}},
  language     = {{ita}},
  number       = {{10}},
  pages        = {{93--489}},
  publisher    = {{Societa Editrice Universo}},
  series       = {{La Clinical terapeutica}},
  title        = {{La citologia esfoliativa congiuntivale nella sindrome di Sjögren}},
  volume       = {{147}},
  year         = {{1996}},
}