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Effect of Branch Stent Choice on Branch-related Outcomes in Complex Aortic Repair.

Mastracci, T M ; Carrell, T ; Constantinou, J ; Dias, Nuno LU orcid ; Martin-Gonzalez, T ; Katsargyris, A ; Modarai, B ; Resch, Tim LU ; Verhoeven, E L G and Burnell, M , et al. (2016) In European journal of vascular and endovascular surgery
Abstract
OBJECTIVES:



The use of branched stent grafts for the treatment of thoracoabdominal aneurysms [TAAA] is increasing, but mating stent graft choice has not been studied. This study combined experience of five high volume centres to assess a preferred mating stent.

METHODS:



Data from five centres were retrospectively combined. Patients were included if they underwent stent graft for treatment of TAAA that used only branches to mate with visceral and renal vessels. All patients with fenestrations in their device were excluded. Perioperative details, reintervention, occlusion, and death were recorded. Outcome of occlusion or reintervention, as well as a composite outcome of any death, occlusion, or... (More)
OBJECTIVES:



The use of branched stent grafts for the treatment of thoracoabdominal aneurysms [TAAA] is increasing, but mating stent graft choice has not been studied. This study combined experience of five high volume centres to assess a preferred mating stent.

METHODS:



Data from five centres were retrospectively combined. Patients were included if they underwent stent graft for treatment of TAAA that used only branches to mate with visceral and renal vessels. All patients with fenestrations in their device were excluded. Perioperative details, reintervention, occlusion, and death were recorded. Outcome of occlusion or reintervention, as well as a composite outcome of any death, occlusion, or reintervention was planned using a per-patient, and per-branch analysis.

RESULTS:



In 235 included patients, there were 940 vessels available for placement of mating stent. The average age of included patients was 70 years (SD 7.9), and 179 of the 235 were male. Medical comorbidities included diabetes in 29/234 (12.4%), current smoker in 81/233 (34.8%), and COPD in 77/234 (32.9%). The primary stent deployed was self-expanding in 556 branches, balloon expandable in 231 branches, and was unknown in 92 branches. After a mean of 20.7 months (SD 25) follow-up, there have been 44 incidents of occlusion or reintervention, of which 40 culprit stents are known. Where the stent placed is known, the event rate in renal branches (35/437, 8%) is higher than that of visceral branches (8/443, 1.8%). There is no difference in occlusion or reintervention between self-expanding and balloon expandable stents (HR 0.95, p = .91) but there is a statistically significant difference between renal and visceral artery occlusions (HR 3.51, p = 0.001).

CONCLUSION:



There appears to be no difference in occlusion or reintervention rate for branch vessels mated with balloon expandable compared with self-expanding stents. Renal events appear to outnumber visceral events in this population. (Less)
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organization
publishing date
type
Contribution to journal
publication status
published
subject
in
European journal of vascular and endovascular surgery
publisher
Elsevier
external identifiers
  • pmid:26916389
  • wos:000374618400016
  • scopus:84961662007
  • pmid:26916389
ISSN
1532-2165
DOI
10.1016/j.ejvs.2015.12.046
language
English
LU publication?
yes
id
4bb94df7-cb2f-4383-85c0-5684e9dded9d (old id 8821604)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/26916389?dopt=Abstract
date added to LUP
2016-04-01 13:40:49
date last changed
2022-04-21 22:53:49
@article{4bb94df7-cb2f-4383-85c0-5684e9dded9d,
  abstract     = {{OBJECTIVES:<br/><br>
<br/><br>
The use of branched stent grafts for the treatment of thoracoabdominal aneurysms [TAAA] is increasing, but mating stent graft choice has not been studied. This study combined experience of five high volume centres to assess a preferred mating stent.<br/><br>
METHODS:<br/><br>
<br/><br>
Data from five centres were retrospectively combined. Patients were included if they underwent stent graft for treatment of TAAA that used only branches to mate with visceral and renal vessels. All patients with fenestrations in their device were excluded. Perioperative details, reintervention, occlusion, and death were recorded. Outcome of occlusion or reintervention, as well as a composite outcome of any death, occlusion, or reintervention was planned using a per-patient, and per-branch analysis.<br/><br>
RESULTS:<br/><br>
<br/><br>
In 235 included patients, there were 940 vessels available for placement of mating stent. The average age of included patients was 70 years (SD 7.9), and 179 of the 235 were male. Medical comorbidities included diabetes in 29/234 (12.4%), current smoker in 81/233 (34.8%), and COPD in 77/234 (32.9%). The primary stent deployed was self-expanding in 556 branches, balloon expandable in 231 branches, and was unknown in 92 branches. After a mean of 20.7 months (SD 25) follow-up, there have been 44 incidents of occlusion or reintervention, of which 40 culprit stents are known. Where the stent placed is known, the event rate in renal branches (35/437, 8%) is higher than that of visceral branches (8/443, 1.8%). There is no difference in occlusion or reintervention between self-expanding and balloon expandable stents (HR 0.95, p = .91) but there is a statistically significant difference between renal and visceral artery occlusions (HR 3.51, p = 0.001).<br/><br>
CONCLUSION:<br/><br>
<br/><br>
There appears to be no difference in occlusion or reintervention rate for branch vessels mated with balloon expandable compared with self-expanding stents. Renal events appear to outnumber visceral events in this population.}},
  author       = {{Mastracci, T M and Carrell, T and Constantinou, J and Dias, Nuno and Martin-Gonzalez, T and Katsargyris, A and Modarai, B and Resch, Tim and Verhoeven, E L G and Burnell, M and Haulon, S}},
  issn         = {{1532-2165}},
  language     = {{eng}},
  month        = {{02}},
  publisher    = {{Elsevier}},
  series       = {{European journal of vascular and endovascular surgery}},
  title        = {{Effect of Branch Stent Choice on Branch-related Outcomes in Complex Aortic Repair.}},
  url          = {{http://dx.doi.org/10.1016/j.ejvs.2015.12.046}},
  doi          = {{10.1016/j.ejvs.2015.12.046}},
  year         = {{2016}},
}