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Prognostic Determinants of Coronary Atherosclerosis in Stable Ischemic Heart Disease : Anatomy, Physiology, or Morphology?

Ahmadi, Amir ; Stone, Gregg W. ; Leipsic, Jonathon ; Shaw, Leslee J. ; Villines, Todd C. ; Kern, Morton J. ; Hecht, Harvey ; Erlinge, David LU orcid ; Ben-Yehuda, Ori and Maehara, Akiko , et al. (2016) In Circulation Research 119(2). p.317-329
Abstract

Risk stratification in patients with stable ischemic heart disease is essential to guide treatment decisions. In this regard, whether coronary anatomy, physiology, or plaque morphology is the best determinant of prognosis (and driver an effective therapeutic risk reduction) remains one of the greatest ongoing debates in cardiology. In the present report, we review the evidence for each of these characteristics and explore potential algorithms that may enable a practical diagnostic and therapeutic strategy for the management of patients with stable ischemic heart disease.

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organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
coronary artery disease, fractional flow reserve, multidetector computed tomography, myocardial ischemia, plaque, atherosclerotic
in
Circulation Research
volume
119
issue
2
pages
13 pages
publisher
Lippincott Williams & Wilkins
external identifiers
  • pmid:27390334
  • wos:000379532300018
  • scopus:84978154344
ISSN
0009-7330
DOI
10.1161/CIRCRESAHA.116.308952
language
English
LU publication?
yes
id
4bde0d7e-5d91-437c-8eba-65beb6fec9ed
date added to LUP
2016-08-02 09:29:45
date last changed
2025-04-04 14:59:13
@article{4bde0d7e-5d91-437c-8eba-65beb6fec9ed,
  abstract     = {{<p>Risk stratification in patients with stable ischemic heart disease is essential to guide treatment decisions. In this regard, whether coronary anatomy, physiology, or plaque morphology is the best determinant of prognosis (and driver an effective therapeutic risk reduction) remains one of the greatest ongoing debates in cardiology. In the present report, we review the evidence for each of these characteristics and explore potential algorithms that may enable a practical diagnostic and therapeutic strategy for the management of patients with stable ischemic heart disease.</p>}},
  author       = {{Ahmadi, Amir and Stone, Gregg W. and Leipsic, Jonathon and Shaw, Leslee J. and Villines, Todd C. and Kern, Morton J. and Hecht, Harvey and Erlinge, David and Ben-Yehuda, Ori and Maehara, Akiko and Arbustini, Eloisa and Serruys, Patrick and Garcia-Garcia, Hector M. and Narula, Jagat}},
  issn         = {{0009-7330}},
  keywords     = {{coronary artery disease; fractional flow reserve; multidetector computed tomography; myocardial ischemia; plaque, atherosclerotic}},
  language     = {{eng}},
  month        = {{07}},
  number       = {{2}},
  pages        = {{317--329}},
  publisher    = {{Lippincott Williams & Wilkins}},
  series       = {{Circulation Research}},
  title        = {{Prognostic Determinants of Coronary Atherosclerosis in Stable Ischemic Heart Disease : Anatomy, Physiology, or Morphology?}},
  url          = {{http://dx.doi.org/10.1161/CIRCRESAHA.116.308952}},
  doi          = {{10.1161/CIRCRESAHA.116.308952}},
  volume       = {{119}},
  year         = {{2016}},
}