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Avoidance of sun exposure as a risk factor for major causes of death : A competing risk analysis of the Melanoma in Southern Sweden cohort

Lindqvist, P. G. LU ; Epstein, E. LU ; Nielsen, K. LU ; Landin-Olsson, M. LU ; Ingvar, C. LU and Olsson, H. LU (2016) In Journal of Internal Medicine1989-01-01+01:00 280(4). p.375-387
Abstract

Objective: Women with active sunlight exposure habits experience a lower mortality rate than women who avoid sun exposure; however, they are at an increased risk of skin cancer. We aimed to explore the differences in main causes of death according to sun exposure. Methods: We assessed the differences in sun exposure as a risk factor for all-cause mortality in a competing risk scenario for 29 518 Swedish women in a prospective 20-year follow-up of the Melanoma in Southern Sweden (MISS) cohort. Women were recruited from 1990 to 1992 (aged 25-64 years at the start of the study). We obtained detailed information at baseline on sun exposure habits and potential confounders. The data were analysed using modern survival statistics. Results:... (More)

Objective: Women with active sunlight exposure habits experience a lower mortality rate than women who avoid sun exposure; however, they are at an increased risk of skin cancer. We aimed to explore the differences in main causes of death according to sun exposure. Methods: We assessed the differences in sun exposure as a risk factor for all-cause mortality in a competing risk scenario for 29 518 Swedish women in a prospective 20-year follow-up of the Melanoma in Southern Sweden (MISS) cohort. Women were recruited from 1990 to 1992 (aged 25-64 years at the start of the study). We obtained detailed information at baseline on sun exposure habits and potential confounders. The data were analysed using modern survival statistics. Results: Women with active sun exposure habits were mainly at a lower risk of cardiovascular disease (CVD) and noncancer/non-CVD death as compared to those who avoided sun exposure. As a result of their increased survival, the relative contribution of cancer death increased in these women. Nonsmokers who avoided sun exposure had a life expectancy similar to smokers in the highest sun exposure group, indicating that avoidance of sun exposure is a risk factor for death of a similar magnitude as smoking. Compared to the highest sun exposure group, life expectancy of avoiders of sun exposure was reduced by 0.6-2.1 years. Conclusion: The longer life expectancy amongst women with active sun exposure habits was related to a decrease in CVD and noncancer/non-CVD mortality, causing the relative contribution of death due to cancer to increase.

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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
CVD, Cigarette smoke, Cohort study, Melanoma, Mortality, Public health, sun exposure
in
Journal of Internal Medicine1989-01-01+01:00
volume
280
issue
4
pages
375 - 387
publisher
Wiley-Blackwell Publishing Ltd
external identifiers
  • wos:000386917000005
  • scopus:84988428079
ISSN
0954-6820
DOI
10.1111/joim.12496
language
English
LU publication?
yes
id
4c3d27ca-2a13-4fd8-9712-514c184adb8f
date added to LUP
2016-05-18 17:13:21
date last changed
2018-07-15 04:31:31
@article{4c3d27ca-2a13-4fd8-9712-514c184adb8f,
  abstract     = {<p>Objective: Women with active sunlight exposure habits experience a lower mortality rate than women who avoid sun exposure; however, they are at an increased risk of skin cancer. We aimed to explore the differences in main causes of death according to sun exposure. Methods: We assessed the differences in sun exposure as a risk factor for all-cause mortality in a competing risk scenario for 29 518 Swedish women in a prospective 20-year follow-up of the Melanoma in Southern Sweden (MISS) cohort. Women were recruited from 1990 to 1992 (aged 25-64 years at the start of the study). We obtained detailed information at baseline on sun exposure habits and potential confounders. The data were analysed using modern survival statistics. Results: Women with active sun exposure habits were mainly at a lower risk of cardiovascular disease (CVD) and noncancer/non-CVD death as compared to those who avoided sun exposure. As a result of their increased survival, the relative contribution of cancer death increased in these women. Nonsmokers who avoided sun exposure had a life expectancy similar to smokers in the highest sun exposure group, indicating that avoidance of sun exposure is a risk factor for death of a similar magnitude as smoking. Compared to the highest sun exposure group, life expectancy of avoiders of sun exposure was reduced by 0.6-2.1 years. Conclusion: The longer life expectancy amongst women with active sun exposure habits was related to a decrease in CVD and noncancer/non-CVD mortality, causing the relative contribution of death due to cancer to increase.</p>},
  author       = {Lindqvist, P. G. and Epstein, E. and Nielsen, K. and Landin-Olsson, M. and Ingvar, C. and Olsson, H.},
  issn         = {0954-6820},
  keyword      = {CVD,Cigarette smoke,Cohort study,Melanoma,Mortality,Public health,sun exposure},
  language     = {eng},
  number       = {4},
  pages        = {375--387},
  publisher    = {Wiley-Blackwell Publishing Ltd},
  series       = {Journal of Internal Medicine1989-01-01+01:00},
  title        = {Avoidance of sun exposure as a risk factor for major causes of death : A competing risk analysis of the Melanoma in Southern Sweden cohort},
  url          = {http://dx.doi.org/10.1111/joim.12496},
  volume       = {280},
  year         = {2016},
}