Solubility and Thermal Degradation of Quercetin in CO2-Expanded Liquids
(2020) In Molecules (Basel, Switzerland) 25(23).- Abstract
The solubility of quercetin and its thermal degradation was studied in CO2-expanded ethanol and ethyl lactate. An equipment setup was constructed that enabled the separation of the products of degradation while quantifying the solubility of quercetin. Three different conditions of temperature were analyzed (308, 323, and 343 K) at 10 MPa. Higher solubility and thermal degradation of quercetin were observed for CO2-expanded ethyl lactate in comparison with CO2-expanded ethanol. At the same time, as the amount of CO2 was increased in the CO2-expanded liquids mixtures, the thermal degradation of quercetin decreased for almost all the conditions of temperature considered in this work. The importance of considering thermal degradation while... (More)
The solubility of quercetin and its thermal degradation was studied in CO2-expanded ethanol and ethyl lactate. An equipment setup was constructed that enabled the separation of the products of degradation while quantifying the solubility of quercetin. Three different conditions of temperature were analyzed (308, 323, and 343 K) at 10 MPa. Higher solubility and thermal degradation of quercetin were observed for CO2-expanded ethyl lactate in comparison with CO2-expanded ethanol. At the same time, as the amount of CO2 was increased in the CO2-expanded liquids mixtures, the thermal degradation of quercetin decreased for almost all the conditions of temperature considered in this work. The importance of considering thermal degradation while performing solubility measurements of compounds that are thermally unstable such as quercetin was highlighted.
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- author
- Cunico, Larissa P. LU ; Cobo, Andrés Medina ; Al-Hamimi, Said LU and Turner, Charlotta LU
- organization
- publishing date
- 2020
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- gas-expanded liquid, green solvent, quercetin, solubility, subcritical fluid, thermal degradation
- in
- Molecules (Basel, Switzerland)
- volume
- 25
- issue
- 23
- article number
- 5582
- publisher
- MDPI AG
- external identifiers
-
- pmid:33261120
- scopus:85097035528
- ISSN
- 1420-3049
- DOI
- 10.3390/molecules25235582
- language
- English
- LU publication?
- yes
- id
- 4d7ace1d-7d98-40b9-b121-a0a4fe346d7c
- date added to LUP
- 2020-12-11 09:31:53
- date last changed
- 2024-04-03 18:39:16
@article{4d7ace1d-7d98-40b9-b121-a0a4fe346d7c,
abstract = {{<p>The solubility of quercetin and its thermal degradation was studied in CO2-expanded ethanol and ethyl lactate. An equipment setup was constructed that enabled the separation of the products of degradation while quantifying the solubility of quercetin. Three different conditions of temperature were analyzed (308, 323, and 343 K) at 10 MPa. Higher solubility and thermal degradation of quercetin were observed for CO2-expanded ethyl lactate in comparison with CO2-expanded ethanol. At the same time, as the amount of CO2 was increased in the CO2-expanded liquids mixtures, the thermal degradation of quercetin decreased for almost all the conditions of temperature considered in this work. The importance of considering thermal degradation while performing solubility measurements of compounds that are thermally unstable such as quercetin was highlighted.</p>}},
author = {{Cunico, Larissa P. and Cobo, Andrés Medina and Al-Hamimi, Said and Turner, Charlotta}},
issn = {{1420-3049}},
keywords = {{gas-expanded liquid; green solvent; quercetin; solubility; subcritical fluid; thermal degradation}},
language = {{eng}},
number = {{23}},
publisher = {{MDPI AG}},
series = {{Molecules (Basel, Switzerland)}},
title = {{Solubility and Thermal Degradation of Quercetin in CO<sub>2</sub>-Expanded Liquids}},
url = {{http://dx.doi.org/10.3390/molecules25235582}},
doi = {{10.3390/molecules25235582}},
volume = {{25}},
year = {{2020}},
}