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An lrp-like gene of Bacillus subtilis involved in branched-chain amino acid transport

Belitsky, B R ; Gustafsson, Mattias LU ; Sonenshein, A L and von Wachenfeldt, Claes LU (1997) In Journal of Bacteriology 179(17). p.5448-5457
Abstract
The azlB locus of Bacillus subtilis was defined previously by a mutation conferring resistance to a leucine analog, 4-azaleucine (J. B. Ward, Jr., and S. A. Zahler, J. Bacteriol. 116:727-735, 1973). In this report, azlB is shown to be the first gene of an operon apparently involved in branched-chain amino acid transport. The product of the azlB gene is an Lrp-like protein that negatively regulates expression of the azlBCDEF operon. Resistance to 4-azaleucine in azlB mutants is due to overproduction of AzlC and AzlD, two novel hydrophobic proteins.
Please use this url to cite or link to this publication:
author
; ; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Journal of Bacteriology
volume
179
issue
17
pages
5448 - 5457
publisher
American Society for Microbiology
external identifiers
  • pmid:9287000
  • scopus:0030885438
ISSN
0021-9193
language
English
LU publication?
yes
id
4e41ad28-a68a-44c9-88fe-3468160150e0 (old id 1111908)
alternative location
http://www.pubmedcentral.nih.gov/articlerender.fcgi?rendertype=abstract&artid=179416
date added to LUP
2016-04-01 11:42:57
date last changed
2025-10-14 13:08:14
@article{4e41ad28-a68a-44c9-88fe-3468160150e0,
  abstract     = {{The azlB locus of Bacillus subtilis was defined previously by a mutation conferring resistance to a leucine analog, 4-azaleucine (J. B. Ward, Jr., and S. A. Zahler, J. Bacteriol. 116:727-735, 1973). In this report, azlB is shown to be the first gene of an operon apparently involved in branched-chain amino acid transport. The product of the azlB gene is an Lrp-like protein that negatively regulates expression of the azlBCDEF operon. Resistance to 4-azaleucine in azlB mutants is due to overproduction of AzlC and AzlD, two novel hydrophobic proteins.}},
  author       = {{Belitsky, B R and Gustafsson, Mattias and Sonenshein, A L and von Wachenfeldt, Claes}},
  issn         = {{0021-9193}},
  language     = {{eng}},
  number       = {{17}},
  pages        = {{5448--5457}},
  publisher    = {{American Society for Microbiology}},
  series       = {{Journal of Bacteriology}},
  title        = {{An lrp-like gene of Bacillus subtilis involved in branched-chain amino acid transport}},
  url          = {{http://www.pubmedcentral.nih.gov/articlerender.fcgi?rendertype=abstract&artid=179416}},
  volume       = {{179}},
  year         = {{1997}},
}