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Parkinson's Disease in a Dish : What Patient Specific-Reprogrammed Somatic Cells Can Tell Us about Parkinson's Disease, If Anything?

Drouin-Ouellet, J LU and Barker, R A LU (2012) In Stem Cells International 2012.
Abstract

Technologies allowing for the derivation of patient-specific neurons from somatic cells are emerging as powerful in vitro tools to investigate the intrinsic cellular pathological behaviours of the diseases that affect these patients. While the use of patient-derived neurons to model Parkinson's disease (PD) has only just begun, these approaches have allowed us to begin investigating disease pathogenesis in a unique way. In this paper, we discuss the advances made in the field of cellular reprogramming to model PD and discuss the pros and cons associated with the use of such cells.

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author
publishing date
type
Contribution to journal
publication status
published
keywords
Journal Article
in
Stem Cells International
volume
2012
pages
10 pages
publisher
Hindawi Publishing Corporation
external identifiers
  • scopus:84872151168
ISSN
1687-966X
DOI
10.1155/2012/926147
language
English
LU publication?
no
id
4e9192ab-b723-41ca-b826-d123aa699a51
date added to LUP
2016-11-22 09:03:41
date last changed
2017-01-01 08:40:19
@article{4e9192ab-b723-41ca-b826-d123aa699a51,
  abstract     = {<p>Technologies allowing for the derivation of patient-specific neurons from somatic cells are emerging as powerful in vitro tools to investigate the intrinsic cellular pathological behaviours of the diseases that affect these patients. While the use of patient-derived neurons to model Parkinson's disease (PD) has only just begun, these approaches have allowed us to begin investigating disease pathogenesis in a unique way. In this paper, we discuss the advances made in the field of cellular reprogramming to model PD and discuss the pros and cons associated with the use of such cells.</p>},
  articleno    = {926147},
  author       = {Drouin-Ouellet, J and Barker, R A},
  issn         = {1687-966X},
  keyword      = {Journal Article},
  language     = {eng},
  pages        = {10},
  publisher    = {Hindawi Publishing Corporation},
  series       = {Stem Cells International},
  title        = {Parkinson's Disease in a Dish : What Patient Specific-Reprogrammed Somatic Cells Can Tell Us about Parkinson's Disease, If Anything?},
  url          = {http://dx.doi.org/10.1155/2012/926147},
  volume       = {2012},
  year         = {2012},
}