Amperometric In Vitro Monitoring of Penetration through Skin Membrane
(2015) In Electroanalysis 27(1). p.111-117- Abstract
- The aim of this study was to demonstrate that penetration of quercetin, hydrogen peroxide and ascorbic acid through skin membranes can be monitored amperometrically. Skin membrane was fixed on the top of chemically modified electrodes and penetration of the appropriate compound was registered as electrode current. The methodology allows the study of penetration from solution as well as from pharmaceutical creams. From real-time measurements of electrode current, fluxes and diffusion coefficients of mentioned compounds in skin membranes have been estimated.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/5069961
- author
- organization
- publishing date
- 2015
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- Penetration, Transdermal delivery, Amperometry, Quercetin, Hydrogen, peroxide, Ascorbic acid, Skin membrane
- in
- Electroanalysis
- volume
- 27
- issue
- 1
- pages
- 111 - 117
- publisher
- John Wiley & Sons Inc.
- external identifiers
-
- wos:000347838300014
- scopus:84920983473
- ISSN
- 1040-0397
- DOI
- 10.1002/elan.201400426
- language
- English
- LU publication?
- yes
- additional info
- The information about affiliations in this record was updated in December 2015. The record was previously connected to the following departments: Analytical Chemistry (S/LTH) (011001004), Cell Pathology (013031400), Food Technology (011001017)
- id
- f8eee49e-9456-407b-9af9-b09c84ad1dd0 (old id 5069961)
- date added to LUP
- 2016-04-01 13:10:08
- date last changed
- 2023-10-14 23:02:07
@article{f8eee49e-9456-407b-9af9-b09c84ad1dd0, abstract = {{The aim of this study was to demonstrate that penetration of quercetin, hydrogen peroxide and ascorbic acid through skin membranes can be monitored amperometrically. Skin membrane was fixed on the top of chemically modified electrodes and penetration of the appropriate compound was registered as electrode current. The methodology allows the study of penetration from solution as well as from pharmaceutical creams. From real-time measurements of electrode current, fluxes and diffusion coefficients of mentioned compounds in skin membranes have been estimated.}}, author = {{Gari, Hala and Rembiesa, Jadwiga and Masilionis, Ignas and Vreva, Naida and Svensson, Birgitta and Sund, Torbjorn and Hansson, Henri and Moren, Anna Karin and Sjöö, Malin and Wahlgren, Marie and Engblom, Johan and Ruzgas, Tautgirdas}}, issn = {{1040-0397}}, keywords = {{Penetration; Transdermal delivery; Amperometry; Quercetin; Hydrogen; peroxide; Ascorbic acid; Skin membrane}}, language = {{eng}}, number = {{1}}, pages = {{111--117}}, publisher = {{John Wiley & Sons Inc.}}, series = {{Electroanalysis}}, title = {{Amperometric In Vitro Monitoring of Penetration through Skin Membrane}}, url = {{http://dx.doi.org/10.1002/elan.201400426}}, doi = {{10.1002/elan.201400426}}, volume = {{27}}, year = {{2015}}, }