Independent validation of metric optimized gating for fetal cardiovascular phase-contrast flow imaging
(2019) In Magnetic Resonance in Medicine 81(1). p.495-503- Abstract
PURPOSE: To validate metric optimized gating phase-contrast MR (MOG PC-MR) flow measurements for a range of fetal flow velocities in phantom experiments. 2) To investigate intra- and interobserver variability for fetal flow measurements at an imaging center other than the original site.
METHODS: MOG PC-MR was compared to timer/beaker measurements in a pulsatile flow phantom using a heart rate (∼145 bpm), nozzle diameter (∼6 mm), and flow range (∼130-700 mL/min) similar to fetal imaging. Fifteen healthy fetuses were included for intra- and interobserver variability in the fetal descending aorta and umbilical vein.
RESULTS: Phantom MOG PC-MR flow bias and variability was 2% ± 23%. Accuracy of MOG PC-MR was degraded for flow... (More)
PURPOSE: To validate metric optimized gating phase-contrast MR (MOG PC-MR) flow measurements for a range of fetal flow velocities in phantom experiments. 2) To investigate intra- and interobserver variability for fetal flow measurements at an imaging center other than the original site.
METHODS: MOG PC-MR was compared to timer/beaker measurements in a pulsatile flow phantom using a heart rate (∼145 bpm), nozzle diameter (∼6 mm), and flow range (∼130-700 mL/min) similar to fetal imaging. Fifteen healthy fetuses were included for intra- and interobserver variability in the fetal descending aorta and umbilical vein.
RESULTS: Phantom MOG PC-MR flow bias and variability was 2% ± 23%. Accuracy of MOG PC-MR was degraded for flow profiles with low velocity-to-noise ratio. Intra- and interobserver coefficients of variation were 6% and 19%, respectively, for fetal descending aorta; and 10% and 17%, respectively, for the umbilical vein.
CONCLUSION: Phantom validation showed good agreement between MOG and conventionally gated PC-MR, except for cases with low velocity-to-noise ratio, which resulted in MOG misgating and underestimated peak velocities and warranted optimization of sequence parameters to individual fetal vessels. Inter- and intraobserver variability for fetal MOG PC-MR imaging were comparable to previously reported values.
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- author
- Bidhult, Sebastian LU ; Töger, Johannes LU ; Heiberg, Einar LU ; Carlsson, Marcus LU ; Arheden, Håkan LU ; Aletras, Anthony H LU and Hedström, Erik LU
- organization
- publishing date
- 2019
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Magnetic Resonance in Medicine
- volume
- 81
- issue
- 1
- pages
- 495 - 503
- publisher
- John Wiley & Sons Inc.
- external identifiers
-
- pmid:30159933
- scopus:85053281500
- ISSN
- 1522-2594
- DOI
- 10.1002/mrm.27392
- language
- English
- LU publication?
- yes
- id
- 5176f8e6-31e8-4780-a004-d09508c248dd
- date added to LUP
- 2018-10-06 07:14:39
- date last changed
- 2024-09-18 03:12:55
@article{5176f8e6-31e8-4780-a004-d09508c248dd, abstract = {{<p>PURPOSE: To validate metric optimized gating phase-contrast MR (MOG PC-MR) flow measurements for a range of fetal flow velocities in phantom experiments. 2) To investigate intra- and interobserver variability for fetal flow measurements at an imaging center other than the original site.</p><p>METHODS: MOG PC-MR was compared to timer/beaker measurements in a pulsatile flow phantom using a heart rate (∼145 bpm), nozzle diameter (∼6 mm), and flow range (∼130-700 mL/min) similar to fetal imaging. Fifteen healthy fetuses were included for intra- and interobserver variability in the fetal descending aorta and umbilical vein.</p><p>RESULTS: Phantom MOG PC-MR flow bias and variability was 2% ± 23%. Accuracy of MOG PC-MR was degraded for flow profiles with low velocity-to-noise ratio. Intra- and interobserver coefficients of variation were 6% and 19%, respectively, for fetal descending aorta; and 10% and 17%, respectively, for the umbilical vein.</p><p>CONCLUSION: Phantom validation showed good agreement between MOG and conventionally gated PC-MR, except for cases with low velocity-to-noise ratio, which resulted in MOG misgating and underestimated peak velocities and warranted optimization of sequence parameters to individual fetal vessels. Inter- and intraobserver variability for fetal MOG PC-MR imaging were comparable to previously reported values.</p>}}, author = {{Bidhult, Sebastian and Töger, Johannes and Heiberg, Einar and Carlsson, Marcus and Arheden, Håkan and Aletras, Anthony H and Hedström, Erik}}, issn = {{1522-2594}}, language = {{eng}}, number = {{1}}, pages = {{495--503}}, publisher = {{John Wiley & Sons Inc.}}, series = {{Magnetic Resonance in Medicine}}, title = {{Independent validation of metric optimized gating for fetal cardiovascular phase-contrast flow imaging}}, url = {{http://dx.doi.org/10.1002/mrm.27392}}, doi = {{10.1002/mrm.27392}}, volume = {{81}}, year = {{2019}}, }