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Incidence of Primary Cancers and Intracranial Tumour Recurrences in Growth Hormone-Treated and Untreated Adult Hypopituitary Patients: Analyses from HypoCCS.

Child, Christopher J; Conroy, Daniel; Zimmermann, Alan G; Woodmansee, Whitney; Erfurth, Eva Marie LU and Robison, Leslie (2015) In European Journal of Endocrinology 172(6). p.779-790
Abstract
Speculation remains that growth hormone (GH) treatment is associated with increased neoplasia risk. Studies in GH-treated childhood cancer survivors suggested higher rates of second neoplasms, while cancer risk data for GH-treated and untreated hypopituitary adults have been variable. We present primary cancer risk data from the Hypopituitary Control and Complications Study (HypoCCS) with a focus on specific cancers, and assessment of recurrence rates for pituitary adenoma (PA) and craniopharyngioma (CP).
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
European Journal of Endocrinology
volume
172
issue
6
pages
779 - 790
publisher
Society of the European Journal of Endocrinology
external identifiers
  • pmid:25810462
  • wos:000357212600022
  • scopus:84930607776
ISSN
1479-683X
DOI
10.1530/EJE-14-1123
language
English
LU publication?
yes
id
9a2dbbb7-cbd7-41e6-9d27-a9ff106a54bf (old id 5257637)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/25810462?dopt=Abstract
date added to LUP
2015-04-04 17:49:45
date last changed
2017-09-17 03:23:25
@article{9a2dbbb7-cbd7-41e6-9d27-a9ff106a54bf,
  abstract     = {Speculation remains that growth hormone (GH) treatment is associated with increased neoplasia risk. Studies in GH-treated childhood cancer survivors suggested higher rates of second neoplasms, while cancer risk data for GH-treated and untreated hypopituitary adults have been variable. We present primary cancer risk data from the Hypopituitary Control and Complications Study (HypoCCS) with a focus on specific cancers, and assessment of recurrence rates for pituitary adenoma (PA) and craniopharyngioma (CP).},
  author       = {Child, Christopher J and Conroy, Daniel and Zimmermann, Alan G and Woodmansee, Whitney and Erfurth, Eva Marie and Robison, Leslie},
  issn         = {1479-683X},
  language     = {eng},
  number       = {6},
  pages        = {779--790},
  publisher    = {Society of the European Journal of Endocrinology},
  series       = {European Journal of Endocrinology},
  title        = {Incidence of Primary Cancers and Intracranial Tumour Recurrences in Growth Hormone-Treated and Untreated Adult Hypopituitary Patients: Analyses from HypoCCS.},
  url          = {http://dx.doi.org/10.1530/EJE-14-1123},
  volume       = {172},
  year         = {2015},
}