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The fat cell epigenetic signature in post-obese women is characterized by global hypomethylation and differential DNA methylation of adipogenesis genes.

Dahlman, I; Sinha, I; Gao, H; Brodin, D; Thorell, A; Rydén, M; Andersson, D P; Henriksson, J; Perfilyev, Alexander LU and Ling, Charlotte LU , et al. (2015) In International Journal of Obesity 39(6). p.910-919
Abstract
Obese subjects have increased number of enlarged fat cells which are reduced in size but not number in post-obesity. We performed DNA methylation profiling in fat cells with the aim of identifying differentially methylated DNA sites (DMS) linked to adipose hyperplasia (many small fat cells) in post-obesity.
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publishing date
type
Contribution to journal
publication status
published
subject
in
International Journal of Obesity
volume
39
issue
6
pages
910 - 919
publisher
Nature Publishing Group
external identifiers
  • pmid:25783037
  • wos:000356039500006
  • scopus:84930764622
ISSN
1476-5497
DOI
10.1038/ijo.2015.31
language
English
LU publication?
yes
id
a83a8492-8a3d-4bfe-b5d1-a1cf942bdb1d (old id 5258315)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/25783037?dopt=Abstract
date added to LUP
2015-04-05 19:21:14
date last changed
2017-11-05 03:03:16
@article{a83a8492-8a3d-4bfe-b5d1-a1cf942bdb1d,
  abstract     = {Obese subjects have increased number of enlarged fat cells which are reduced in size but not number in post-obesity. We performed DNA methylation profiling in fat cells with the aim of identifying differentially methylated DNA sites (DMS) linked to adipose hyperplasia (many small fat cells) in post-obesity.},
  author       = {Dahlman, I and Sinha, I and Gao, H and Brodin, D and Thorell, A and Rydén, M and Andersson, D P and Henriksson, J and Perfilyev, Alexander and Ling, Charlotte and Dahlman-Wright, K and Arner, P},
  issn         = {1476-5497},
  language     = {eng},
  number       = {6},
  pages        = {910--919},
  publisher    = {Nature Publishing Group},
  series       = {International Journal of Obesity},
  title        = {The fat cell epigenetic signature in post-obese women is characterized by global hypomethylation and differential DNA methylation of adipogenesis genes.},
  url          = {http://dx.doi.org/10.1038/ijo.2015.31},
  volume       = {39},
  year         = {2015},
}