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ATG16L1 Expression in Carotid Atherosclerotic Plaques Is Associated With Plaque Vulnerability.

Magné, Joelle; Gustafsson, Peter; Jin, Hong; Maegdefessel, Lars; Hultenby, Kjell; Wernerson, Annika; Eriksson, Per; Franco-Cereceda, Anders; Kovanen, Petri T and Goncalves, Isabel LU , et al. (2015) In Arteriosclerosis, Thrombosis and Vascular Biology 35(5). p.1226-1235
Abstract
Autophagy has emerged as a cell survival mechanism critical for cellular homeostasis, which may play a protective role in atherosclerosis. ATG16L1, a protein essential for early stages of autophagy, has been implicated in the pathogenesis of Crohn's disease. However, it is unknown whether ATG16L1 is involved in atherosclerosis. Our aim was to analyze ATG16L1 expression in carotid atherosclerotic plaques in relation to markers of plaque vulnerability.
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Contribution to journal
publication status
published
subject
in
Arteriosclerosis, Thrombosis and Vascular Biology
volume
35
issue
5
pages
1226 - 1235
publisher
American Heart Association
external identifiers
  • pmid:25767270
  • wos:000353335300021
  • scopus:84933074128
ISSN
1524-4636
DOI
10.1161/ATVBAHA.114.304840
language
English
LU publication?
yes
id
9ed33af3-8cee-4c4f-b2bb-46ca76bf922a (old id 5261663)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/25767270?dopt=Abstract
date added to LUP
2015-04-03 18:25:18
date last changed
2017-07-02 03:00:33
@article{9ed33af3-8cee-4c4f-b2bb-46ca76bf922a,
  abstract     = {Autophagy has emerged as a cell survival mechanism critical for cellular homeostasis, which may play a protective role in atherosclerosis. ATG16L1, a protein essential for early stages of autophagy, has been implicated in the pathogenesis of Crohn's disease. However, it is unknown whether ATG16L1 is involved in atherosclerosis. Our aim was to analyze ATG16L1 expression in carotid atherosclerotic plaques in relation to markers of plaque vulnerability.},
  author       = {Magné, Joelle and Gustafsson, Peter and Jin, Hong and Maegdefessel, Lars and Hultenby, Kjell and Wernerson, Annika and Eriksson, Per and Franco-Cereceda, Anders and Kovanen, Petri T and Goncalves, Isabel and Ehrenborg, Ewa},
  issn         = {1524-4636},
  language     = {eng},
  number       = {5},
  pages        = {1226--1235},
  publisher    = {American Heart Association},
  series       = {Arteriosclerosis, Thrombosis and Vascular Biology},
  title        = {ATG16L1 Expression in Carotid Atherosclerotic Plaques Is Associated With Plaque Vulnerability.},
  url          = {http://dx.doi.org/10.1161/ATVBAHA.114.304840},
  volume       = {35},
  year         = {2015},
}