Presence of High-Risk HPV mRNA in Relation to Future High-Grade Lesions among High-Risk HPV DNA Positive Women with Minor Cytological Abnormalities.
(2015) In PLoS ONE 10(4).- Abstract
- Continuous expression of E6- and E7-oncogenes of high-risk human papillomavirus (HPV) types is necessary for the development and maintenance of the dysplastic phenotype. The aim of the study was to determine the sensitivity and specificity of the APTIMA HPV mRNA assay (Hologic) in predicting future development of high-grade cervical intraepithelial neoplasia (CIN) among high-risk HPV-DNA-positive women with atypical squamous cells of undetermined significance (ASCUS) or low-grade squamous epithelial lesion (LSIL) cytology.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/5341218
- author
- Johansson, Hanna K LU ; Bjelkenkrantz, Kaj LU ; Darlin, Lotten LU ; Dillner, Joakim LU and Forslund, Ola LU
- organization
- publishing date
- 2015
- type
- Contribution to journal
- publication status
- published
- subject
- in
- PLoS ONE
- volume
- 10
- issue
- 4
- article number
- e0124460
- publisher
- Public Library of Science (PLoS)
- external identifiers
-
- pmid:25893988
- wos:000353211700096
- scopus:84929485283
- pmid:25893988
- ISSN
- 1932-6203
- DOI
- 10.1371/journal.pone.0124460
- language
- English
- LU publication?
- yes
- id
- 6cda242e-2841-487f-83af-3e001820c58a (old id 5341218)
- alternative location
- http://www.ncbi.nlm.nih.gov/pubmed/25893988?dopt=Abstract
- date added to LUP
- 2016-04-01 13:09:04
- date last changed
- 2022-05-15 02:50:26
@article{6cda242e-2841-487f-83af-3e001820c58a, abstract = {{Continuous expression of E6- and E7-oncogenes of high-risk human papillomavirus (HPV) types is necessary for the development and maintenance of the dysplastic phenotype. The aim of the study was to determine the sensitivity and specificity of the APTIMA HPV mRNA assay (Hologic) in predicting future development of high-grade cervical intraepithelial neoplasia (CIN) among high-risk HPV-DNA-positive women with atypical squamous cells of undetermined significance (ASCUS) or low-grade squamous epithelial lesion (LSIL) cytology.}}, author = {{Johansson, Hanna K and Bjelkenkrantz, Kaj and Darlin, Lotten and Dillner, Joakim and Forslund, Ola}}, issn = {{1932-6203}}, language = {{eng}}, number = {{4}}, publisher = {{Public Library of Science (PLoS)}}, series = {{PLoS ONE}}, title = {{Presence of High-Risk HPV mRNA in Relation to Future High-Grade Lesions among High-Risk HPV DNA Positive Women with Minor Cytological Abnormalities.}}, url = {{https://lup.lub.lu.se/search/files/3188231/7697274}}, doi = {{10.1371/journal.pone.0124460}}, volume = {{10}}, year = {{2015}}, }