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Dietary ω-3 polyunsaturated fatty acids decrease retinal neovascularization by adipose-endoplasmic reticulum stress reduction to increase adiponectin.

Fu, Zhongjie ; Lofqvist, Chatarina A ; Shao, Zhuo ; Sun, Ye ; Joyal, Jean-Sebastien ; Hurst, Christian G ; Cui, Ricky Z ; Evans, Lucy P ; Tian, Katherine and SanGiovanni, John Paul , et al. (2015) In American Journal of Clinical Nutrition 101(4). p.879-888
Abstract
Retinopathy of prematurity (ROP) is a vision-threatening disease in premature infants. Serum adiponectin (APN) concentrations positively correlate with postnatal growth and gestational age, important risk factors for ROP development. Dietary ω-3 (n-3) long-chain polyunsaturated fatty acids (ω-3 LCPUFAs) suppress ROP and oxygen-induced retinopathy (OIR) in a mouse model of human ROP, but the mechanism is not fully understood.
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organization
publishing date
type
Contribution to journal
publication status
published
subject
in
American Journal of Clinical Nutrition
volume
101
issue
4
pages
879 - 888
publisher
Oxford University Press
external identifiers
  • pmid:25833984
  • wos:000352336000023
  • scopus:84929658689
  • pmid:25833984
ISSN
1938-3207
DOI
10.3945/ajcn.114.099291
language
English
LU publication?
yes
id
49bd4a8c-386e-4d91-b6e7-8f7bddc174c1 (old id 5360194)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/25833984?dopt=Abstract
date added to LUP
2016-04-01 10:34:44
date last changed
2023-08-31 05:53:19
@article{49bd4a8c-386e-4d91-b6e7-8f7bddc174c1,
  abstract     = {{Retinopathy of prematurity (ROP) is a vision-threatening disease in premature infants. Serum adiponectin (APN) concentrations positively correlate with postnatal growth and gestational age, important risk factors for ROP development. Dietary ω-3 (n-3) long-chain polyunsaturated fatty acids (ω-3 LCPUFAs) suppress ROP and oxygen-induced retinopathy (OIR) in a mouse model of human ROP, but the mechanism is not fully understood.}},
  author       = {{Fu, Zhongjie and Lofqvist, Chatarina A and Shao, Zhuo and Sun, Ye and Joyal, Jean-Sebastien and Hurst, Christian G and Cui, Ricky Z and Evans, Lucy P and Tian, Katherine and SanGiovanni, John Paul and Chen, Jing and Ley, David and Pupp, Ingrid and Hellström, Ann and Smith, Lois Eh}},
  issn         = {{1938-3207}},
  language     = {{eng}},
  number       = {{4}},
  pages        = {{879--888}},
  publisher    = {{Oxford University Press}},
  series       = {{American Journal of Clinical Nutrition}},
  title        = {{Dietary ω-3 polyunsaturated fatty acids decrease retinal neovascularization by adipose-endoplasmic reticulum stress reduction to increase adiponectin.}},
  url          = {{http://dx.doi.org/10.3945/ajcn.114.099291}},
  doi          = {{10.3945/ajcn.114.099291}},
  volume       = {{101}},
  year         = {{2015}},
}