An improved probing controller for substrate feeding in fed-batch culteres of E. coli: simulations and experiments
(2002) 8th IFAC International Conference on Computer Applications in Biotechnology (CAB8) p.213-218- Abstract
- A strategy for feedback control of the glucose feed rate in cultivations of E.coli is discussed. By making probing pulses in the feedrate it is possible to detect and avoid undesirable by-productformation using a standard dissolved oxygen sensor. The feasibility of an improved and simplified probing algorithm is demonstrated by simulations as well as laboratory-scale experiments.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/537890
- author
- Åkesson, Mats ; Hagander, Per LU and Axelsson, Jan Peter
- organization
- publishing date
- 2002
- type
- Chapter in Book/Report/Conference proceeding
- publication status
- published
- subject
- keywords
- Fermentation process, probing, extremum control, process control
- host publication
- Computer Applications in Biotechnology 2001
- pages
- 213 - 218
- publisher
- Elsevier
- conference name
- 8th IFAC International Conference on Computer Applications in Biotechnology (CAB8)
- conference location
- Quebeq City, Canada
- conference dates
- 2001-06-24 - 2001-06-27
- external identifiers
-
- wos:000177564700037
- ISBN
- 0080436811
- language
- English
- LU publication?
- yes
- id
- 4edaf96b-3832-485f-9cec-60f80a23645c (old id 537890)
- date added to LUP
- 2016-04-04 11:08:28
- date last changed
- 2019-12-11 09:36:39
@inproceedings{4edaf96b-3832-485f-9cec-60f80a23645c, abstract = {{A strategy for feedback control of the glucose feed rate in cultivations of E.coli is discussed. By making probing pulses in the feedrate it is possible to detect and avoid undesirable by-productformation using a standard dissolved oxygen sensor. The feasibility of an improved and simplified probing algorithm is demonstrated by simulations as well as laboratory-scale experiments.}}, author = {{Åkesson, Mats and Hagander, Per and Axelsson, Jan Peter}}, booktitle = {{Computer Applications in Biotechnology 2001}}, isbn = {{0080436811}}, keywords = {{Fermentation process; probing; extremum control; process control}}, language = {{eng}}, pages = {{213--218}}, publisher = {{Elsevier}}, title = {{An improved probing controller for substrate feeding in fed-batch culteres of E. coli: simulations and experiments}}, year = {{2002}}, }