Beyond genotype-phenotype maps : Toward a phenotype-centered perspective on evolution
(2022) In BioEssays 44(9).- Abstract
Evolutionary biology is paying increasing attention to the mechanisms that enable phenotypic plasticity, evolvability, and extra-genetic inheritance. Yet, there is a concern that these phenomena remain insufficiently integrated within evolutionary theory. Understanding their evolutionary implications would require focusing on phenotypes and their variation, but this does not always fit well with the prevalent genetic representation of evolution that screens off developmental mechanisms. Here, we instead use development as a starting point, and represent it in a way that allows genetic, environmental and epigenetic sources of phenotypic variation to be independent. We show why this representation helps to understand the evolutionary... (More)
Evolutionary biology is paying increasing attention to the mechanisms that enable phenotypic plasticity, evolvability, and extra-genetic inheritance. Yet, there is a concern that these phenomena remain insufficiently integrated within evolutionary theory. Understanding their evolutionary implications would require focusing on phenotypes and their variation, but this does not always fit well with the prevalent genetic representation of evolution that screens off developmental mechanisms. Here, we instead use development as a starting point, and represent it in a way that allows genetic, environmental and epigenetic sources of phenotypic variation to be independent. We show why this representation helps to understand the evolutionary consequences of both genetic and non-genetic phenotype determinants, and discuss how this approach can instigate future areas of empirical and theoretical research.
(Less)
- author
- Brun-Usan, Miguel LU ; Zimm, Roland and Uller, Tobias LU
- organization
- publishing date
- 2022
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- conceptual framework, development, evolutionary theory, evolvability, genotype-phenotype map, maternal effects, phenotypic plasticity
- in
- BioEssays
- volume
- 44
- issue
- 9
- article number
- 2100225
- publisher
- John Wiley & Sons Inc.
- external identifiers
-
- scopus:85134614736
- pmid:35863907
- ISSN
- 0265-9247
- DOI
- 10.1002/bies.202100225
- language
- English
- LU publication?
- yes
- id
- 53bb6a84-a575-4435-8a61-2120f7c793d8
- date added to LUP
- 2022-09-05 09:06:38
- date last changed
- 2024-06-13 18:43:22
@article{53bb6a84-a575-4435-8a61-2120f7c793d8,
abstract = {{<p>Evolutionary biology is paying increasing attention to the mechanisms that enable phenotypic plasticity, evolvability, and extra-genetic inheritance. Yet, there is a concern that these phenomena remain insufficiently integrated within evolutionary theory. Understanding their evolutionary implications would require focusing on phenotypes and their variation, but this does not always fit well with the prevalent genetic representation of evolution that screens off developmental mechanisms. Here, we instead use development as a starting point, and represent it in a way that allows genetic, environmental and epigenetic sources of phenotypic variation to be independent. We show why this representation helps to understand the evolutionary consequences of both genetic and non-genetic phenotype determinants, and discuss how this approach can instigate future areas of empirical and theoretical research.</p>}},
author = {{Brun-Usan, Miguel and Zimm, Roland and Uller, Tobias}},
issn = {{0265-9247}},
keywords = {{conceptual framework; development; evolutionary theory; evolvability; genotype-phenotype map; maternal effects; phenotypic plasticity}},
language = {{eng}},
number = {{9}},
publisher = {{John Wiley & Sons Inc.}},
series = {{BioEssays}},
title = {{Beyond genotype-phenotype maps : Toward a phenotype-centered perspective on evolution}},
url = {{http://dx.doi.org/10.1002/bies.202100225}},
doi = {{10.1002/bies.202100225}},
volume = {{44}},
year = {{2022}},
}