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Quantification of the absorbed dose in 3D by means of advanced optical diagnostics based on structured illumination

Kristensson, Elias LU ; Ceberg, Sofie LU ; Bäck, Sven LU and Jordan, Kevin (2015) 8th International Conference on 3D Radiation Dosimetry (IC3DDose) In 8th International Conference on 3D Radiation Dosimetry (IC3DDOSE) 573. p.012010-012010
Abstract
The purpose of this study was to present a novel optical diagnostic tool that corrects for undesired contribution of multiply scattered light, thus opening up for e.g. quantitative optical CT measurements of opaque samples. The approach is based on a technique called Structured Illumination (SI), which is commonly employed within microscopic imaging to enhance the depth-resolution. The concept of SI applies for many types of source-detector arrangements and the configuration employed in this paper relies on side-scattering detection. A nPAG polymer gel phantom was irradiated using 6 MV beam. Three-dimensional information was obtained by translating the sample perpendicular to the direction of light, thus sequentially probing different... (More)
The purpose of this study was to present a novel optical diagnostic tool that corrects for undesired contribution of multiply scattered light, thus opening up for e.g. quantitative optical CT measurements of opaque samples. The approach is based on a technique called Structured Illumination (SI), which is commonly employed within microscopic imaging to enhance the depth-resolution. The concept of SI applies for many types of source-detector arrangements and the configuration employed in this paper relies on side-scattering detection. A nPAG polymer gel phantom was irradiated using 6 MV beam. Three-dimensional information was obtained by translating the sample perpendicular to the direction of light, thus sequentially probing different sections. These were then stacked together to form a 3D representation of the sample. By altering the polarization of the laser light during the data acquisition it was discovered that the aggregates responsible for the scattering of light followed Rayleigh scattering, implying that their individual sizes are smaller than, or in the order of, 500 nm. (Less)
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author
organization
publishing date
type
Chapter in Book/Report/Conference proceeding
publication status
published
subject
in
8th International Conference on 3D Radiation Dosimetry (IC3DDOSE)
volume
573
pages
012010 - 012010
publisher
IOP Publishing
conference name
8th International Conference on 3D Radiation Dosimetry (IC3DDose)
external identifiers
  • wos:000352600500010
  • scopus:84946206531
ISSN
1742-6596
1742-6588
DOI
10.1088/1742-6596/573/1/012010
language
English
LU publication?
yes
id
04d9ed9c-b63a-4381-89ed-ecd4c134dffc (old id 5402750)
date added to LUP
2015-05-19 13:18:22
date last changed
2017-07-23 03:25:30
@inproceedings{04d9ed9c-b63a-4381-89ed-ecd4c134dffc,
  abstract     = {The purpose of this study was to present a novel optical diagnostic tool that corrects for undesired contribution of multiply scattered light, thus opening up for e.g. quantitative optical CT measurements of opaque samples. The approach is based on a technique called Structured Illumination (SI), which is commonly employed within microscopic imaging to enhance the depth-resolution. The concept of SI applies for many types of source-detector arrangements and the configuration employed in this paper relies on side-scattering detection. A nPAG polymer gel phantom was irradiated using 6 MV beam. Three-dimensional information was obtained by translating the sample perpendicular to the direction of light, thus sequentially probing different sections. These were then stacked together to form a 3D representation of the sample. By altering the polarization of the laser light during the data acquisition it was discovered that the aggregates responsible for the scattering of light followed Rayleigh scattering, implying that their individual sizes are smaller than, or in the order of, 500 nm.},
  author       = {Kristensson, Elias and Ceberg, Sofie and Bäck, Sven and Jordan, Kevin},
  booktitle    = {8th International Conference on 3D Radiation Dosimetry (IC3DDOSE)},
  issn         = {1742-6596},
  language     = {eng},
  pages        = {012010--012010},
  publisher    = {IOP Publishing},
  title        = {Quantification of the absorbed dose in 3D by means of advanced optical diagnostics based on structured illumination},
  url          = {http://dx.doi.org/10.1088/1742-6596/573/1/012010},
  volume       = {573},
  year         = {2015},
}