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TERT promoter mutations: a novel independent prognostic factor in primary glioblastomas.

Simon, Matthias ; Hosen, Ismail ; Gousias, Konstantinos ; Rachakonda, Sivaramakrishna ; Heidenreich, Barbara ; Gessi, Marco ; Schramm, Johannes ; Hemminki, Kari LU ; Waha, Andreas and Kumar, Rajiv (2015) In Neuro-Oncology 17(1). p.45-52
Abstract
Activating somatic mutations in the promoter region of the telomerase reverse transcriptase gene (TERT) have been detected in several cancers. In this study we investigated the TERT promoter mutations and their impact on patient survival in World Health Organization grade IV glioblastoma multiforme (GBM).
Please use this url to cite or link to this publication:
author
; ; ; ; ; ; ; ; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Neuro-Oncology
volume
17
issue
1
pages
45 - 52
publisher
Oxford University Press
external identifiers
  • pmid:25140036
  • wos:000350138000006
  • scopus:84922513709
  • pmid:25140036
ISSN
1523-5866
DOI
10.1093/neuonc/nou158
language
English
LU publication?
yes
id
551ffafa-2320-4604-8b8a-733b368e5a77 (old id 4614252)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/25140036?dopt=Abstract
date added to LUP
2016-04-01 10:34:52
date last changed
2022-04-20 03:24:11
@article{551ffafa-2320-4604-8b8a-733b368e5a77,
  abstract     = {{Activating somatic mutations in the promoter region of the telomerase reverse transcriptase gene (TERT) have been detected in several cancers. In this study we investigated the TERT promoter mutations and their impact on patient survival in World Health Organization grade IV glioblastoma multiforme (GBM).}},
  author       = {{Simon, Matthias and Hosen, Ismail and Gousias, Konstantinos and Rachakonda, Sivaramakrishna and Heidenreich, Barbara and Gessi, Marco and Schramm, Johannes and Hemminki, Kari and Waha, Andreas and Kumar, Rajiv}},
  issn         = {{1523-5866}},
  language     = {{eng}},
  number       = {{1}},
  pages        = {{45--52}},
  publisher    = {{Oxford University Press}},
  series       = {{Neuro-Oncology}},
  title        = {{TERT promoter mutations: a novel independent prognostic factor in primary glioblastomas.}},
  url          = {{https://lup.lub.lu.se/search/files/1963439/8147409}},
  doi          = {{10.1093/neuonc/nou158}},
  volume       = {{17}},
  year         = {{2015}},
}