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Bradycardia During Targeted Temperature Management: An Early Marker of Lower Mortality and Favorable Neurologic Outcome in Comatose Out-of-Hospital Cardiac Arrest Patients.

Thomsen, Jakob Hartvig ; Nielsen, Niklas LU ; Hassager, Christian ; Wanscher, Michael ; Pehrson, Steen ; Køber, Lars ; Bro-Jeppesen, John ; Søholm, Helle ; Winther-Jensen, Matilde and Pellis, Tommaso , et al. (2016) In Critical Care Medicine 44(2). p.308-318
Abstract
Bradycardia is common during targeted temperature management, likely being a physiologic response to lower body temperature, and has recently been associated with favorable outcome following out-of-hospital cardiac arrest in smaller observational studies. The present study sought to confirm this finding in a large multicenter cohort of patients treated with targeted temperature management at 33°C and explore the response to targeted temperature management targeting 36°C.
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organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Critical Care Medicine
volume
44
issue
2
pages
308 - 318
publisher
Lippincott Williams & Wilkins
external identifiers
  • pmid:26468897
  • wos:000368503700009
  • scopus:84954330342
  • pmid:26468897
ISSN
1530-0293
DOI
10.1097/CCM.0000000000001390
language
English
LU publication?
yes
id
55532dea-4bca-4f5f-8717-41cc5ce5facf (old id 8152195)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/26468897?dopt=Abstract
date added to LUP
2016-04-01 10:16:29
date last changed
2022-03-12 03:56:31
@article{55532dea-4bca-4f5f-8717-41cc5ce5facf,
  abstract     = {{Bradycardia is common during targeted temperature management, likely being a physiologic response to lower body temperature, and has recently been associated with favorable outcome following out-of-hospital cardiac arrest in smaller observational studies. The present study sought to confirm this finding in a large multicenter cohort of patients treated with targeted temperature management at 33°C and explore the response to targeted temperature management targeting 36°C.}},
  author       = {{Thomsen, Jakob Hartvig and Nielsen, Niklas and Hassager, Christian and Wanscher, Michael and Pehrson, Steen and Køber, Lars and Bro-Jeppesen, John and Søholm, Helle and Winther-Jensen, Matilde and Pellis, Tommaso and Kuiper, Michael and Erlinge, David and Friberg, Hans and Kjaergaard, Jesper}},
  issn         = {{1530-0293}},
  language     = {{eng}},
  number       = {{2}},
  pages        = {{308--318}},
  publisher    = {{Lippincott Williams & Wilkins}},
  series       = {{Critical Care Medicine}},
  title        = {{Bradycardia During Targeted Temperature Management: An Early Marker of Lower Mortality and Favorable Neurologic Outcome in Comatose Out-of-Hospital Cardiac Arrest Patients.}},
  url          = {{http://dx.doi.org/10.1097/CCM.0000000000001390}},
  doi          = {{10.1097/CCM.0000000000001390}},
  volume       = {{44}},
  year         = {{2016}},
}