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Towards prevention of breast cancer : What are the clinical challenges?

Borgquist, Signe LU ; Hall, Per; Lipkus, Isaac and Garber, Judy E. (2018) In Cancer Prevention Research 11(5). p.255-264
Abstract

The dramatic increase in breast cancer incidence compels a paradigm shift in our preventive efforts. There are several barriers to overcome before prevention becomes an established part of breast cancer management. The objective of this review is to identify the clinical challenges for improved breast cancer prevention and discuss current knowledge on breast cancer risk assessment methods, risk communication, ethics, and interventional efforts with the aim of covering the aspects relevant for a breast cancer prevention trial. Herein, the following five areas are discussed: (i) Adequate tools for identification of women at high risk of breast cancer suggestively entitled Prevent! Online. (ii) Consensus on the definition of high risk,... (More)

The dramatic increase in breast cancer incidence compels a paradigm shift in our preventive efforts. There are several barriers to overcome before prevention becomes an established part of breast cancer management. The objective of this review is to identify the clinical challenges for improved breast cancer prevention and discuss current knowledge on breast cancer risk assessment methods, risk communication, ethics, and interventional efforts with the aim of covering the aspects relevant for a breast cancer prevention trial. Herein, the following five areas are discussed: (i) Adequate tools for identification of women at high risk of breast cancer suggestively entitled Prevent! Online. (ii) Consensus on the definition of high risk, which is regarded as mandatory for all risk communication and potential prophylactic interventions. (iii) Risk perception and communication regarding risk information. (iv) Potential ethical concerns relevant for future breast cancer prevention programs. (v) Risk-reducing programs involving multileveled prevention depending on identified risk. Taken together, devoted efforts from both policy makers and health care providers are warranted to improve risk assessment and risk counseling in women at risk for breast cancer to optimize the prevention of breast cancer.

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organization
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Contribution to journal
publication status
published
subject
in
Cancer Prevention Research
volume
11
issue
5
pages
10 pages
publisher
American Association for Cancer Research
external identifiers
  • scopus:85047774268
ISSN
1940-6207
DOI
language
English
LU publication?
yes
id
55bb597f-bf21-441e-9694-6bde99777533
date added to LUP
2018-06-14 13:43:14
date last changed
2018-06-15 03:00:02
@article{55bb597f-bf21-441e-9694-6bde99777533,
  abstract     = {<p>The dramatic increase in breast cancer incidence compels a paradigm shift in our preventive efforts. There are several barriers to overcome before prevention becomes an established part of breast cancer management. The objective of this review is to identify the clinical challenges for improved breast cancer prevention and discuss current knowledge on breast cancer risk assessment methods, risk communication, ethics, and interventional efforts with the aim of covering the aspects relevant for a breast cancer prevention trial. Herein, the following five areas are discussed: (i) Adequate tools for identification of women at high risk of breast cancer suggestively entitled Prevent! Online. (ii) Consensus on the definition of high risk, which is regarded as mandatory for all risk communication and potential prophylactic interventions. (iii) Risk perception and communication regarding risk information. (iv) Potential ethical concerns relevant for future breast cancer prevention programs. (v) Risk-reducing programs involving multileveled prevention depending on identified risk. Taken together, devoted efforts from both policy makers and health care providers are warranted to improve risk assessment and risk counseling in women at risk for breast cancer to optimize the prevention of breast cancer.</p>},
  author       = {Borgquist, Signe and Hall, Per and Lipkus, Isaac and Garber, Judy E.},
  issn         = {1940-6207},
  language     = {eng},
  month        = {05},
  number       = {5},
  pages        = {255--264},
  publisher    = {American Association for Cancer Research},
  series       = {Cancer Prevention Research},
  title        = {Towards prevention of breast cancer : What are the clinical challenges?},
  url          = {http://dx.doi.org/},
  volume       = {11},
  year         = {2018},
}