Advanced

Is familial risk for depression confounded by individual and familial socioeconomic factors and neighborhood environmental factors? A 7-year follow-up study in Sweden

Hamano, Tsuyoshi; Li, Xinjun LU ; Lönn, Sara Larsson LU ; Nabika, Toru; Sundquist, Jan LU and Sundquist, Kristina LU (2018) In Psychiatry Research 266. p.30-35
Abstract

Family history of depression is an important risk factor for depression. The aim of this study was to examine whether the effect of family history of depression is confounded by individual and familial socioeconomic factors (i.e., country of origin, educational attainment, family income and mobility) and neighborhood environmental factors (i.e., neighborhood deprivation and neighborhood social capital). The study population comprised 188,907 individuals aged 20–44 years from a nationwide sample of primary care centers in Sweden. Among these individuals, 22,014 with a first event of depression (6,486 men and 15,528 women) were identified during the 7-year follow-up period. Family history of depression was defined as depression in at... (More)

Family history of depression is an important risk factor for depression. The aim of this study was to examine whether the effect of family history of depression is confounded by individual and familial socioeconomic factors (i.e., country of origin, educational attainment, family income and mobility) and neighborhood environmental factors (i.e., neighborhood deprivation and neighborhood social capital). The study population comprised 188,907 individuals aged 20–44 years from a nationwide sample of primary care centers in Sweden. Among these individuals, 22,014 with a first event of depression (6,486 men and 15,528 women) were identified during the 7-year follow-up period. Family history of depression was defined as depression in at least one parent. Cross-classified multilevel logistic regression models were used to calculate odds ratios with 95% credible intervals. Increased familial odds were observed after adjustment for individual and familial socioeconomic factors and neighborhood environmental factors for both men and women. Our results suggest that family history of depression is an independent risk factor for depression. Offspring of parents with depression are important targets for disease prevention, regardless of individual and familial socioeconomic factors and neighborhood environmental factors.

(Less)
Please use this url to cite or link to this publication:
author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Depression, Familial risk, Follow-up study, Multilevel analysis
in
Psychiatry Research
volume
266
pages
6 pages
publisher
Elsevier
external identifiers
  • scopus:85047275993
ISSN
0165-1781
DOI
10.1016/j.psychres.2018.05.041
language
English
LU publication?
yes
id
56e312d5-5177-4e21-b52d-a6c9b2405b9e
date added to LUP
2018-05-31 14:16:51
date last changed
2019-04-05 14:56:18
@article{56e312d5-5177-4e21-b52d-a6c9b2405b9e,
  abstract     = {<p>Family history of depression is an important risk factor for depression. The aim of this study was to examine whether the effect of family history of depression is confounded by individual and familial socioeconomic factors (i.e., country of origin, educational attainment, family income and mobility) and neighborhood environmental factors (i.e., neighborhood deprivation and neighborhood social capital). The study population comprised 188,907 individuals aged 20–44 years from a nationwide sample of primary care centers in Sweden. Among these individuals, 22,014 with a first event of depression (6,486 men and 15,528 women) were identified during the 7-year follow-up period. Family history of depression was defined as depression in at least one parent. Cross-classified multilevel logistic regression models were used to calculate odds ratios with 95% credible intervals. Increased familial odds were observed after adjustment for individual and familial socioeconomic factors and neighborhood environmental factors for both men and women. Our results suggest that family history of depression is an independent risk factor for depression. Offspring of parents with depression are important targets for disease prevention, regardless of individual and familial socioeconomic factors and neighborhood environmental factors.</p>},
  author       = {Hamano, Tsuyoshi and Li, Xinjun and Lönn, Sara Larsson and Nabika, Toru and Sundquist, Jan and Sundquist, Kristina},
  issn         = {0165-1781},
  keyword      = {Depression,Familial risk,Follow-up study,Multilevel analysis},
  language     = {eng},
  month        = {08},
  pages        = {30--35},
  publisher    = {Elsevier},
  series       = {Psychiatry Research},
  title        = {Is familial risk for depression confounded by individual and familial socioeconomic factors and neighborhood environmental factors? A 7-year follow-up study in Sweden},
  url          = {http://dx.doi.org/10.1016/j.psychres.2018.05.041},
  volume       = {266},
  year         = {2018},
}