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Genomics of stroke recovery and outcome

Lindgren, Arne G. LU (2025) In Journal of Cerebral Blood Flow and Metabolism
Abstract

The understanding of genomics has improved tremendously during the last decades. The concept of recovery and outcome after stroke has also progressed during this time. However, the connection between genomics and stroke recovery has only begun to emerge in a more structural and comprehensive way. Different types of outcomes and recovery occur after stroke. This depends on domain of neurological deficit, severity, resilience, receptivity for rehabilitation measures, and concomitant morbidity. Methods for assessing stroke patients’ prognosis depend on these factors. Different genetic approaches are possible and there is an increasing need for linking genetic findings to other omics as well as to clinically meaningful results. This review... (More)

The understanding of genomics has improved tremendously during the last decades. The concept of recovery and outcome after stroke has also progressed during this time. However, the connection between genomics and stroke recovery has only begun to emerge in a more structural and comprehensive way. Different types of outcomes and recovery occur after stroke. This depends on domain of neurological deficit, severity, resilience, receptivity for rehabilitation measures, and concomitant morbidity. Methods for assessing stroke patients’ prognosis depend on these factors. Different genetic approaches are possible and there is an increasing need for linking genetic findings to other omics as well as to clinically meaningful results. This review addresses recent advances and views in clinical genomics of stroke recovery and outcome in humans with focus on current and previous studies, concepts, and future perspectives.

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Please use this url to cite or link to this publication:
author
organization
publishing date
type
Contribution to journal
publication status
epub
subject
keywords
Genetics, genomics, outcome, recovery, stroke
in
Journal of Cerebral Blood Flow and Metabolism
publisher
Nature Publishing Group
external identifiers
  • pmid:40215404
  • scopus:105002468774
ISSN
0271-678X
DOI
10.1177/0271678X251332528
language
English
LU publication?
yes
id
57516960-6a2f-409e-b939-a59819f62dfb
date added to LUP
2025-09-01 10:56:50
date last changed
2025-09-02 03:00:07
@article{57516960-6a2f-409e-b939-a59819f62dfb,
  abstract     = {{<p>The understanding of genomics has improved tremendously during the last decades. The concept of recovery and outcome after stroke has also progressed during this time. However, the connection between genomics and stroke recovery has only begun to emerge in a more structural and comprehensive way. Different types of outcomes and recovery occur after stroke. This depends on domain of neurological deficit, severity, resilience, receptivity for rehabilitation measures, and concomitant morbidity. Methods for assessing stroke patients’ prognosis depend on these factors. Different genetic approaches are possible and there is an increasing need for linking genetic findings to other omics as well as to clinically meaningful results. This review addresses recent advances and views in clinical genomics of stroke recovery and outcome in humans with focus on current and previous studies, concepts, and future perspectives.</p>}},
  author       = {{Lindgren, Arne G.}},
  issn         = {{0271-678X}},
  keywords     = {{Genetics; genomics; outcome; recovery; stroke}},
  language     = {{eng}},
  publisher    = {{Nature Publishing Group}},
  series       = {{Journal of Cerebral Blood Flow and Metabolism}},
  title        = {{Genomics of stroke recovery and outcome}},
  url          = {{http://dx.doi.org/10.1177/0271678X251332528}},
  doi          = {{10.1177/0271678X251332528}},
  year         = {{2025}},
}