Advanced

Different Visual Weighting due to Fast or Slow Vestibular Deafferentation : Before and after Schwannoma Surgery

Tjernström, Fredrik LU ; Fransson, Per Anders LU ; Kahlon, Babar LU ; Karlberg, Mikael LU ; Lindberg, Sven LU ; Siesjö, Peter LU and Magnusson, Mans LU (2019) In Neural Plasticity 2019.
Abstract

Background: Feedback postural control depends upon information from somatosensation, vision, and the vestibular system that are weighted depending on their relative importance within the central nervous system. Following loss of any sensory component, the weighting changes, e.g., when suffering a vestibular loss, the most common notion is that patients become more dependent on visual cues for maintaining postural control. Dizziness and disequilibrium are common after surgery in schwannoma patients, which could be due to interpretation of the remaining sensory systems involved in feedback-dependent postural control and spatial orientation.

Objective: To compare visual dependency in spatial orientation and postural control in... (More)

Background: Feedback postural control depends upon information from somatosensation, vision, and the vestibular system that are weighted depending on their relative importance within the central nervous system. Following loss of any sensory component, the weighting changes, e.g., when suffering a vestibular loss, the most common notion is that patients become more dependent on visual cues for maintaining postural control. Dizziness and disequilibrium are common after surgery in schwannoma patients, which could be due to interpretation of the remaining sensory systems involved in feedback-dependent postural control and spatial orientation.

Objective: To compare visual dependency in spatial orientation and postural control in patients suffering from unilateral vestibular loss within different time frames.

Methods: Patients scheduled for schwannoma surgery: group 1 (n = 27) with no vestibular function prior to surgery (lost through years), group 2 (n = 12) with remaining vestibular function at the time of surgery (fast deafferentation), and group 3 (n = 18) with remaining function that was lost through gentamicin installations in the middle ear (slow deafferentation). All patients performed vibratory posturography and rod and frame investigation before surgery and 6 months after surgery.

Results: Postural control improved after surgery in patients that suffered a slow deafferentation (groups 1 and 3) (p < 0.001). Patients that suffered fast loss of remaining vestibular function (group 2) became less visual field dependent after surgery (p ≤ 0.035) and were less able to maintain stability compared with group 1 (p = 0.010) and group 3 (p = 0.010).

Conclusions: The nature and time course of vestibular deafferentation influence the weighting of remaining sensory systems in order to maintain postural control and spatial orientation.

(Less)
Please use this url to cite or link to this publication:
author
publishing date
type
Contribution to journal
publication status
published
subject
in
Neural Plasticity
volume
2019
publisher
Hindawi Publishing Corporation
external identifiers
  • scopus:85062491162
ISSN
2090-5904
DOI
10.1155/2019/4826238
language
English
LU publication?
no
id
5775fed6-e568-46a0-b74b-844d252b28d9
date added to LUP
2019-03-18 14:13:53
date last changed
2019-04-10 04:21:16
@article{5775fed6-e568-46a0-b74b-844d252b28d9,
  abstract     = {<p>Background: Feedback postural control depends upon information from somatosensation, vision, and the vestibular system that are weighted depending on their relative importance within the central nervous system. Following loss of any sensory component, the weighting changes, e.g., when suffering a vestibular loss, the most common notion is that patients become more dependent on visual cues for maintaining postural control. Dizziness and disequilibrium are common after surgery in schwannoma patients, which could be due to interpretation of the remaining sensory systems involved in feedback-dependent postural control and spatial orientation.</p><p>Objective: To compare visual dependency in spatial orientation and postural control in patients suffering from unilateral vestibular loss within different time frames.</p><p>Methods: Patients scheduled for schwannoma surgery: group 1 (n = 27) with no vestibular function prior to surgery (lost through years), group 2 (n = 12) with remaining vestibular function at the time of surgery (fast deafferentation), and group 3 (n = 18) with remaining function that was lost through gentamicin installations in the middle ear (slow deafferentation). All patients performed vibratory posturography and rod and frame investigation before surgery and 6 months after surgery.</p><p>Results: Postural control improved after surgery in patients that suffered a slow deafferentation (groups 1 and 3) (p &lt; 0.001). Patients that suffered fast loss of remaining vestibular function (group 2) became less visual field dependent after surgery (p ≤ 0.035) and were less able to maintain stability compared with group 1 (p = 0.010) and group 3 (p = 0.010).</p><p>Conclusions: The nature and time course of vestibular deafferentation influence the weighting of remaining sensory systems in order to maintain postural control and spatial orientation.</p>},
  articleno    = {4826238},
  author       = {Tjernström, Fredrik and Fransson, Per Anders and Kahlon, Babar and Karlberg, Mikael and Lindberg, Sven and Siesjö, Peter and Magnusson, Mans},
  issn         = {2090-5904},
  language     = {eng},
  publisher    = {Hindawi Publishing Corporation},
  series       = {Neural Plasticity},
  title        = {Different Visual Weighting due to Fast or Slow Vestibular Deafferentation : Before and after Schwannoma Surgery},
  url          = {http://dx.doi.org/10.1155/2019/4826238},
  volume       = {2019},
  year         = {2019},
}