A note on the interpretation of the gamma evaluation index
Ceberg, Crister LU
(2013)
7th International Conference on 3D Radiation Dosimetry (IC3DDose)
444.
p.012082-012082
- Abstract
- The gamma evaluation method has become the gold standard for the comparison between measured and calculated absorbed dose distributions. However, test criteria and failure rate tolerance levels have hitherto normally been based on empirical evidence, rather than rigorous statistical analysis. In this work, it is proposed that the gamma-evaluation method could be reinterpreted such that the absorbed dose difference and distance-to-agreement criteria are replaced by the standard deviations of the associated uncertainties. By comparison between absorbed dose calculations and simulated measurements for clinically realistic test cases in 1D and 2D, it is then shown that the resulting squared gamma distribution follows a chi-squared distribution... (More)
- The gamma evaluation method has become the gold standard for the comparison between measured and calculated absorbed dose distributions. However, test criteria and failure rate tolerance levels have hitherto normally been based on empirical evidence, rather than rigorous statistical analysis. In this work, it is proposed that the gamma-evaluation method could be reinterpreted such that the absorbed dose difference and distance-to-agreement criteria are replaced by the standard deviations of the associated uncertainties. By comparison between absorbed dose calculations and simulated measurements for clinically realistic test cases in 1D and 2D, it is then shown that the resulting squared gamma distribution follows a chi-squared distribution with one degree of freedom. This result can be used to test the statistical significance of measured deviations, and to determine proper failure rate tolerance levels in clinical radiotherapy quality control. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/4027068
- author
- Ceberg, Crister
LU
- organization
- publishing date
- 2013
- type
- Chapter in Book/Report/Conference proceeding
- publication status
- published
- subject
- host publication
- 7th International Conference on 3D Radiation Dosimetry (IC3DDose)
- volume
- 444
- pages
- 012082 - 012082
- publisher
- IOP Publishing
- conference name
- 7th International Conference on 3D Radiation Dosimetry (IC3DDose)
- conference location
- Sydney, Australia
- conference dates
- 2012-11-04 - 2012-11-08
- external identifiers
-
- wos:000322968600082
- scopus:84883401432
- ISSN
- 1742-6588
- 1742-6596
- DOI
- 10.1088/1742-6596/444/1/012082
- language
- English
- LU publication?
- yes
- id
- 57e0f74e-f938-4ffd-8bd1-d0c9ff69ae97 (old id 4027068)
- date added to LUP
- 2016-04-01 10:58:00
- date last changed
- 2024-01-07 05:26:27
@inproceedings{57e0f74e-f938-4ffd-8bd1-d0c9ff69ae97,
abstract = {{The gamma evaluation method has become the gold standard for the comparison between measured and calculated absorbed dose distributions. However, test criteria and failure rate tolerance levels have hitherto normally been based on empirical evidence, rather than rigorous statistical analysis. In this work, it is proposed that the gamma-evaluation method could be reinterpreted such that the absorbed dose difference and distance-to-agreement criteria are replaced by the standard deviations of the associated uncertainties. By comparison between absorbed dose calculations and simulated measurements for clinically realistic test cases in 1D and 2D, it is then shown that the resulting squared gamma distribution follows a chi-squared distribution with one degree of freedom. This result can be used to test the statistical significance of measured deviations, and to determine proper failure rate tolerance levels in clinical radiotherapy quality control.}},
author = {{Ceberg, Crister}},
booktitle = {{7th International Conference on 3D Radiation Dosimetry (IC3DDose)}},
issn = {{1742-6588}},
language = {{eng}},
pages = {{012082--012082}},
publisher = {{IOP Publishing}},
title = {{A note on the interpretation of the gamma evaluation index}},
url = {{http://dx.doi.org/10.1088/1742-6596/444/1/012082}},
doi = {{10.1088/1742-6596/444/1/012082}},
volume = {{444}},
year = {{2013}},
}