RosettaRemodel: A Generalized Framework for Flexible Backbone Protein Design
(2011) In PLoS ONE 6(8).- Abstract
- We describe RosettaRemodel, a generalized framework for flexible protein design that provides a versatile and convenient interface to the Rosetta modeling suite. RosettaRemodel employs a unified interface, called a blueprint, which allows detailed control over many aspects of flexible backbone protein design calculations. RosettaRemodel allows the construction and elaboration of customized protocols for a wide range of design problems ranging from loop insertion and deletion, disulfide engineering, domain assembly, loop remodeling, motif grafting, symmetrical units, to de novo structure modeling.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/2183618
- author
- Huang, Po-Ssu ; Ban, Yih-En Andrew ; Richter, Florian ; André, Ingemar LU ; Vernon, Robert ; Schief, William R. and Baker, David
- organization
- publishing date
- 2011
- type
- Contribution to journal
- publication status
- published
- subject
- in
- PLoS ONE
- volume
- 6
- issue
- 8
- publisher
- Public Library of Science (PLoS)
- external identifiers
-
- wos:000294680800055
- scopus:80052334922
- pmid:21909381
- ISSN
- 1932-6203
- DOI
- 10.1371/journal.pone.0024109
- language
- English
- LU publication?
- yes
- id
- 581e61a0-9c5e-43a0-bf9e-7699edf38395 (old id 2183618)
- date added to LUP
- 2016-04-01 14:33:17
- date last changed
- 2022-04-22 03:46:35
@article{581e61a0-9c5e-43a0-bf9e-7699edf38395, abstract = {{We describe RosettaRemodel, a generalized framework for flexible protein design that provides a versatile and convenient interface to the Rosetta modeling suite. RosettaRemodel employs a unified interface, called a blueprint, which allows detailed control over many aspects of flexible backbone protein design calculations. RosettaRemodel allows the construction and elaboration of customized protocols for a wide range of design problems ranging from loop insertion and deletion, disulfide engineering, domain assembly, loop remodeling, motif grafting, symmetrical units, to de novo structure modeling.}}, author = {{Huang, Po-Ssu and Ban, Yih-En Andrew and Richter, Florian and André, Ingemar and Vernon, Robert and Schief, William R. and Baker, David}}, issn = {{1932-6203}}, language = {{eng}}, number = {{8}}, publisher = {{Public Library of Science (PLoS)}}, series = {{PLoS ONE}}, title = {{RosettaRemodel: A Generalized Framework for Flexible Backbone Protein Design}}, url = {{http://dx.doi.org/10.1371/journal.pone.0024109}}, doi = {{10.1371/journal.pone.0024109}}, volume = {{6}}, year = {{2011}}, }