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Scatterer size estimation using the center frequency assessed from ultrasound time domain data

Erlöv, Tobias LU ; Jansson, Tomas LU ; Persson, Hans W. LU and Cinthio, Magnus LU (2016) In Journal of the Acoustical Society of America 140(4). p.2352-2357
Abstract

Scatterer size estimation is useful when characterizing tissue using ultrasound. In all previous studies on scatterer size, the estimations are performed in the frequency domain and are thus subjected to a trade off in time-frequency resolution. This study focused on the feasibility of estimating scatterer size in the time domain using only the ultrasound center frequency, assuming a Gaussian-shaped pulse. A model for frequency normalization was derived and the frequency-dependent attenuation was compensated. Five phantoms with well-defined sizes of spherical glass beads were made and scanned with two different linear array transducers with variable center frequencies. A strong correlation (r = 0.99, p < 10-19) between the... (More)

Scatterer size estimation is useful when characterizing tissue using ultrasound. In all previous studies on scatterer size, the estimations are performed in the frequency domain and are thus subjected to a trade off in time-frequency resolution. This study focused on the feasibility of estimating scatterer size in the time domain using only the ultrasound center frequency, assuming a Gaussian-shaped pulse. A model for frequency normalization was derived and the frequency-dependent attenuation was compensated. Five phantoms with well-defined sizes of spherical glass beads were made and scanned with two different linear array transducers with variable center frequencies. A strong correlation (r = 0.99, p < 10-19) between the backscattered center frequency and the product between the wave number and scatterer radius was demonstrated. On average the scatterer diameter was underestimated by 6% ± 24%. These results suggest that estimation of scatterer size is possible using only the center frequency assessed in the time domain.

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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Journal of the Acoustical Society of America
volume
140
issue
4
pages
6 pages
publisher
American Institute of Physics
external identifiers
  • scopus:84990856253
  • wos:000387260600026
ISSN
0001-4966
DOI
10.1121/1.4964107
language
English
LU publication?
yes
id
58d2d0b4-f4c0-4046-863e-a76372709324
date added to LUP
2016-11-16 11:04:52
date last changed
2017-01-01 08:39:45
@article{58d2d0b4-f4c0-4046-863e-a76372709324,
  abstract     = {<p>Scatterer size estimation is useful when characterizing tissue using ultrasound. In all previous studies on scatterer size, the estimations are performed in the frequency domain and are thus subjected to a trade off in time-frequency resolution. This study focused on the feasibility of estimating scatterer size in the time domain using only the ultrasound center frequency, assuming a Gaussian-shaped pulse. A model for frequency normalization was derived and the frequency-dependent attenuation was compensated. Five phantoms with well-defined sizes of spherical glass beads were made and scanned with two different linear array transducers with variable center frequencies. A strong correlation (r = 0.99, p &lt; 10<sup>-19</sup>) between the backscattered center frequency and the product between the wave number and scatterer radius was demonstrated. On average the scatterer diameter was underestimated by 6% ± 24%. These results suggest that estimation of scatterer size is possible using only the center frequency assessed in the time domain.</p>},
  author       = {Erlöv, Tobias and Jansson, Tomas and Persson, Hans W. and Cinthio, Magnus},
  issn         = {0001-4966},
  language     = {eng},
  month        = {10},
  number       = {4},
  pages        = {2352--2357},
  publisher    = {American Institute of Physics},
  series       = {Journal of the Acoustical Society of America},
  title        = {Scatterer size estimation using the center frequency assessed from ultrasound time domain data},
  url          = {http://dx.doi.org/10.1121/1.4964107},
  volume       = {140},
  year         = {2016},
}