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Diffusion MRI and Poroelastic Biomechanics of Articular Cartilage

Topgaard, Daniel LU (2017) In Biophysics and Biochemistry of Cartilage by NMR and MRI 2017-January(8). p.375-394
Abstract

Cartilage is a poroelastic material for which application of load leads to fluid flow within and out from the porous solid matrix. The redistribution of fluids is a major factor in determining the mechanical properties and friction coefficients, which consequently depend in a complex way on the details of the load history and geometry. Although current poroelastic models for cartilage generally agree with the observed macroscopic behavior, critical tests of the underlying assumptions require direct measurements of the translational motion of the pore fluids. This chapter reviews magnetic resonance imaging investigations of water diffusion and flow in cartilage, with special emphasis on time-resolved measurements during dynamic... (More)

Cartilage is a poroelastic material for which application of load leads to fluid flow within and out from the porous solid matrix. The redistribution of fluids is a major factor in determining the mechanical properties and friction coefficients, which consequently depend in a complex way on the details of the load history and geometry. Although current poroelastic models for cartilage generally agree with the observed macroscopic behavior, critical tests of the underlying assumptions require direct measurements of the translational motion of the pore fluids. This chapter reviews magnetic resonance imaging investigations of water diffusion and flow in cartilage, with special emphasis on time-resolved measurements during dynamic loading.

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Please use this url to cite or link to this publication:
author
organization
publishing date
type
Chapter in Book/Report/Conference proceeding
publication status
published
subject
in
Biophysics and Biochemistry of Cartilage by NMR and MRI
volume
2017-January
issue
8
pages
20 pages
publisher
Royal Society of Chemistry
external identifiers
  • scopus:85006351864
ISSN
20442548
2044253X
DOI
10.1039/9781782623663-00373
language
English
LU publication?
yes
id
58f5a656-2b9d-4408-9ad8-6865732eed96
date added to LUP
2017-01-23 08:52:18
date last changed
2018-01-07 11:46:07
@inbook{58f5a656-2b9d-4408-9ad8-6865732eed96,
  abstract     = {<p>Cartilage is a poroelastic material for which application of load leads to fluid flow within and out from the porous solid matrix. The redistribution of fluids is a major factor in determining the mechanical properties and friction coefficients, which consequently depend in a complex way on the details of the load history and geometry. Although current poroelastic models for cartilage generally agree with the observed macroscopic behavior, critical tests of the underlying assumptions require direct measurements of the translational motion of the pore fluids. This chapter reviews magnetic resonance imaging investigations of water diffusion and flow in cartilage, with special emphasis on time-resolved measurements during dynamic loading.</p>},
  author       = {Topgaard, Daniel},
  issn         = {20442548},
  language     = {eng},
  number       = {8},
  pages        = {375--394},
  publisher    = {Royal Society of Chemistry},
  series       = {Biophysics and Biochemistry of Cartilage by NMR and MRI},
  title        = {Diffusion MRI and Poroelastic Biomechanics of Articular Cartilage},
  url          = {http://dx.doi.org/10.1039/9781782623663-00373},
  volume       = {2017-January},
  year         = {2017},
}