Comparison of the multi-phasic longitudinal displacement of the left and right common carotid artery in healthy humans
Zhu, Yuxiang LU ; Cinthio, Magnus LU ; Erlöv, Tobias LU ; Bjarnegård, Niclas and Ahlgren, Åsa Rydén LU
(2021)
In Clinical Physiology and Functional Imaging
41(4).
p.342-354
- Abstract
During the cardiac cycle, there is a multi-phasic bidirectional longitudinal movement (LMov) of the intima-media complex of large arteries, i.e. along the arteries. On the left side the common carotid artery (CCA) arises directly from the aortic arc, whereas on the right side the CCA originate from the innominate artery. The aim of this study was to compare LMov of the left and right CCA of healthy subjects to investigate whether the difference in anatomy are of importance for LMov. The CCA's of 93 healthy subjects were investigated using in-house developed ultrasound methods. Although the basic pattern were the same in the majority of subjects, several phases of LMov were significantly larger on the left side (the first retrograde... (More)
During the cardiac cycle, there is a multi-phasic bidirectional longitudinal movement (LMov) of the intima-media complex of large arteries, i.e. along the arteries. On the left side the common carotid artery (CCA) arises directly from the aortic arc, whereas on the right side the CCA originate from the innominate artery. The aim of this study was to compare LMov of the left and right CCA of healthy subjects to investigate whether the difference in anatomy are of importance for LMov. The CCA's of 93 healthy subjects were investigated using in-house developed ultrasound methods. Although the basic pattern were the same in the majority of subjects, several phases of LMov were significantly larger on the left side (the first retrograde phase, p=00006; the second antegrade, "returning" phase, p<0.00001; and the rapid retrograde phase of movement at the end of the cardiac cycle, p<0.000001). In contrast, no significant side-difference in the amplitude of the first antegrade movement was seen. The maximal (peak-to-peak) LMov was significantly larger on the left side (p=0.002). The side differences found seem to increase with aging, and may be related to the difference in anatomy, including possible difference in distance to the heart and especially the presence of an extra bifurcation on the right side. Our data provide an important base for the further study of the relation between the longitudinal movement and atherosclerosis and atherosclerotic plaques.
(Less)
- author
- Zhu, Yuxiang
LU
; Cinthio, Magnus
LU
; Erlöv, Tobias
LU
; Bjarnegård, Niclas
and Ahlgren, Åsa Rydén
LU
- organization
- publishing date
- 2021-07-01
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- longitudinal motion, diameter change, axial displacement, arterial wall, ultrasound
- in
- Clinical Physiology and Functional Imaging
- volume
- 41
- issue
- 4
- pages
- 13 pages
- publisher
- John Wiley & Sons Inc.
- external identifiers
-
- pmid:33763958
- scopus:85104397795
- ISSN
- 1475-0961
- DOI
- 10.1111/cpf.12701
- language
- English
- LU publication?
- yes
- id
- 5977cd74-4e44-4dd9-9b5c-4260a5ce1480
- date added to LUP
- 2021-03-26 09:47:58
- date last changed
- 2024-06-15 08:27:11
@article{5977cd74-4e44-4dd9-9b5c-4260a5ce1480,
abstract = {{<p>During the cardiac cycle, there is a multi-phasic bidirectional longitudinal movement (LMov) of the intima-media complex of large arteries, i.e. along the arteries. On the left side the common carotid artery (CCA) arises directly from the aortic arc, whereas on the right side the CCA originate from the innominate artery. The aim of this study was to compare LMov of the left and right CCA of healthy subjects to investigate whether the difference in anatomy are of importance for LMov. The CCA's of 93 healthy subjects were investigated using in-house developed ultrasound methods. Although the basic pattern were the same in the majority of subjects, several phases of LMov were significantly larger on the left side (the first retrograde phase, p=00006; the second antegrade, "returning" phase, p<0.00001; and the rapid retrograde phase of movement at the end of the cardiac cycle, p<0.000001). In contrast, no significant side-difference in the amplitude of the first antegrade movement was seen. The maximal (peak-to-peak) LMov was significantly larger on the left side (p=0.002). The side differences found seem to increase with aging, and may be related to the difference in anatomy, including possible difference in distance to the heart and especially the presence of an extra bifurcation on the right side. Our data provide an important base for the further study of the relation between the longitudinal movement and atherosclerosis and atherosclerotic plaques.</p>}},
author = {{Zhu, Yuxiang and Cinthio, Magnus and Erlöv, Tobias and Bjarnegård, Niclas and Ahlgren, Åsa Rydén}},
issn = {{1475-0961}},
keywords = {{longitudinal motion; diameter change; axial displacement; arterial wall; ultrasound}},
language = {{eng}},
month = {{07}},
number = {{4}},
pages = {{342--354}},
publisher = {{John Wiley & Sons Inc.}},
series = {{Clinical Physiology and Functional Imaging}},
title = {{Comparison of the multi-phasic longitudinal displacement of the left and right common carotid artery in healthy humans}},
url = {{http://dx.doi.org/10.1111/cpf.12701}},
doi = {{10.1111/cpf.12701}},
volume = {{41}},
year = {{2021}},
}