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Shape-based particle sorting - A new paradigm in microfluidics

Beech, Jason P. LU and Tegenfeldt, Jonas O. LU orcid (2009) 13th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2009 p.800-802
Abstract

Conventional fractionation techniques fail to fully benefit from the variety in morphology and shape that is found among biological particles. Although light scattering in conventional FACS gives some information on the size and morphology of a particle, it is generally not capable of giving a definite number on specified dimensions of a small object. We demonstrate an approach where we select which dimension of a particular object is used to determine its trajectory through an obstacle course and thereby sort not merely with respect to hydrodynamic radius but rather with respect to e.g. thickness, length or width.

Please use this url to cite or link to this publication:
author
and
organization
publishing date
type
Chapter in Book/Report/Conference proceeding
publication status
published
keywords
Deterministic lateral displacement, Separation, Shape
host publication
Proceedings of Conference, MicroTAS 2009 - The 13th International Conference on Miniaturized Systems for Chemistry and Life Sciences
pages
3 pages
publisher
Chemical and Biological Microsystems Society
conference name
13th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2009
conference location
Jeju, Korea, Republic of
conference dates
2009-11-01 - 2009-11-05
external identifiers
  • scopus:84884379960
ISBN
9780979806421
language
English
LU publication?
yes
id
59aa1a27-2345-46bc-9573-98ae6f797573
date added to LUP
2018-10-20 10:28:35
date last changed
2021-06-08 02:15:06
@inproceedings{59aa1a27-2345-46bc-9573-98ae6f797573,
  abstract     = {<p>Conventional fractionation techniques fail to fully benefit from the variety in morphology and shape that is found among biological particles. Although light scattering in conventional FACS gives some information on the size and morphology of a particle, it is generally not capable of giving a definite number on specified dimensions of a small object. We demonstrate an approach where we select which dimension of a particular object is used to determine its trajectory through an obstacle course and thereby sort not merely with respect to hydrodynamic radius but rather with respect to e.g. thickness, length or width.</p>},
  author       = {Beech, Jason P. and Tegenfeldt, Jonas O.},
  booktitle    = {Proceedings of Conference, MicroTAS 2009 - The 13th International Conference on Miniaturized Systems for Chemistry and Life Sciences},
  isbn         = {9780979806421},
  language     = {eng},
  month        = {01},
  pages        = {800--802},
  publisher    = {Chemical and Biological Microsystems Society},
  title        = {Shape-based particle sorting - A new paradigm in microfluidics},
  year         = {2009},
}