ARGET ATRP based surface-imprinted polymer-ordered mesoporous silica composites for selective chloramphenicol adsorption
Mohamed Idris, Zulkarnain ; Enche Ab Rahim, Siti Kartini ; Hameed, Bassim H. ; Ye, Lei LU
and Mohd Din, Azam Taufik
(2025)
In Carbon Research
4(1).
- Abstract
This study introduces a novel approach for synthesising a surface-imprinted polymer-ordered mesoporous silica adsorbent, known as SiO2@MIPs-CAPcr, with high selectivity for chloramphenicol (CAP) adsorption by employing an activator that was regenerated by electron atom transfer radical polymerisation (ARGET ATRP). Optimal synthesising conditions for SiO2@MIPs-CAPcr have been determined, including catalyst ratios, reaction temperature, and reaction time. The prepared silica initiator (SiO2@Br) was confirmed using XRD, SEM, and HRTEM, which revealed uniform spherical nanoparticles with a high specific surface area (638.31 m2.g−1) and total pore volume (0.4152... (More)
This study introduces a novel approach for synthesising a surface-imprinted polymer-ordered mesoporous silica adsorbent, known as SiO2@MIPs-CAPcr, with high selectivity for chloramphenicol (CAP) adsorption by employing an activator that was regenerated by electron atom transfer radical polymerisation (ARGET ATRP). Optimal synthesising conditions for SiO2@MIPs-CAPcr have been determined, including catalyst ratios, reaction temperature, and reaction time. The prepared silica initiator (SiO2@Br) was confirmed using XRD, SEM, and HRTEM, which revealed uniform spherical nanoparticles with a high specific surface area (638.31 m2.g−1) and total pore volume (0.4152 cm3.g−1). FTIR, TGA, TEM, and XRD analyses confirmed successful grafting of the MIPs layer onto SiO2@Br, which reduced the surface area and pore volume of SiO2@MIPs-CAPcr. Under optimised batch adsorption conditions, as analysed using the Sips model, the maximum chloramphenicol (CAP) adsorption capacity of 19.68 mg.g−1 was observed, following a pseudo-second order kinetic model, with thermodynamic analysis indicating a spontaneous, exothermic process. SiO2@MIPs-CAPcr displayed high selectivity for chloramphenicol (CAP) over thiamphenicol (TAP) and ciprofloxacin (CIP), along with a minimal 6.87% decrease in adsorption capacity after four regeneration cycles, demonstrating both strong specificity and good reusability. These findings highlight the effectiveness of ARGET ATRP in engineering tailored adsorbents for environmental and pharmaceutical applications.
(Less)
- author
- Mohamed Idris, Zulkarnain
; Enche Ab Rahim, Siti Kartini
; Hameed, Bassim H.
; Ye, Lei
LU
and Mohd Din, Azam Taufik
- organization
- publishing date
- 2025-12
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- Adsorption, ARGET ATRP, Chloramphenicol, Molecularly imprinted polymer, Precipitation polymerisation
- in
- Carbon Research
- volume
- 4
- issue
- 1
- article number
- 69
- publisher
- Springer Nature
- external identifiers
-
- scopus:105021478640
- DOI
- 10.1007/s44246-025-00233-5
- language
- English
- LU publication?
- yes
- id
- 59d7b276-30a0-416a-a25e-927a05d4a292
- date added to LUP
- 2026-01-12 14:13:21
- date last changed
- 2026-01-12 14:13:40
@article{59d7b276-30a0-416a-a25e-927a05d4a292,
abstract = {{<p>This study introduces a novel approach for synthesising a surface-imprinted polymer-ordered mesoporous silica adsorbent, known as SiO<sub>2</sub>@MIPs-CAPcr, with high selectivity for chloramphenicol (CAP) adsorption by employing an activator that was regenerated by electron atom transfer radical polymerisation (ARGET ATRP). Optimal synthesising conditions for SiO<sub>2</sub>@MIPs-CAPcr have been determined, including catalyst ratios, reaction temperature, and reaction time. The prepared silica initiator (SiO<sub>2</sub>@Br) was confirmed using XRD, SEM, and HRTEM, which revealed uniform spherical nanoparticles with a high specific surface area (638.31 m<sup>2</sup>.g<sup>−1</sup>) and total pore volume (0.4152 cm<sup>3</sup>.g<sup>−1</sup>). FTIR, TGA, TEM, and XRD analyses confirmed successful grafting of the MIPs layer onto SiO<sub>2</sub>@Br, which reduced the surface area and pore volume of SiO<sub>2</sub>@MIPs-CAPcr. Under optimised batch adsorption conditions, as analysed using the Sips model, the maximum chloramphenicol (CAP) adsorption capacity of 19.68 mg.g<sup>−1</sup> was observed, following a pseudo-second order kinetic model, with thermodynamic analysis indicating a spontaneous, exothermic process. SiO<sub>2</sub>@MIPs-CAPcr displayed high selectivity for chloramphenicol (CAP) over thiamphenicol (TAP) and ciprofloxacin (CIP), along with a minimal 6.87% decrease in adsorption capacity after four regeneration cycles, demonstrating both strong specificity and good reusability. These findings highlight the effectiveness of ARGET ATRP in engineering tailored adsorbents for environmental and pharmaceutical applications.</p>}},
author = {{Mohamed Idris, Zulkarnain and Enche Ab Rahim, Siti Kartini and Hameed, Bassim H. and Ye, Lei and Mohd Din, Azam Taufik}},
keywords = {{Adsorption; ARGET ATRP; Chloramphenicol; Molecularly imprinted polymer; Precipitation polymerisation}},
language = {{eng}},
number = {{1}},
publisher = {{Springer Nature}},
series = {{Carbon Research}},
title = {{ARGET ATRP based surface-imprinted polymer-ordered mesoporous silica composites for selective chloramphenicol adsorption}},
url = {{http://dx.doi.org/10.1007/s44246-025-00233-5}},
doi = {{10.1007/s44246-025-00233-5}},
volume = {{4}},
year = {{2025}},
}