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Dehydration inhibits matrix synthesis and cell proliferation : An in vitro study of rabbit flexor tendons

Abrahamsson, Sven Olof LU ; Lohmander, L. Stefan LU orcid and Lundborg, Göran LU (1991) In Acta Orthopaedica 62(2). p.159-162
Abstract

Segments of the deep flexor tendon of the rabbit were exposed to air; the effects of dehydration on in vitro synthesis of proteoglycan, collagen, non-collagenous protein, and cell proliferation were compared with tendon segments that were kept moist with physiologic saline. After 20 min of expo-sure to air, the tendons lost half and after 40 min all of their ability to synthesize matrix components and to proliferate, whereas irrigated tendons remained viable during the entire experiment.

Please use this url to cite or link to this publication:
author
; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Acta Orthopaedica
volume
62
issue
2
pages
4 pages
publisher
Taylor & Francis
external identifiers
  • scopus:0025963345
  • pmid:2014727
ISSN
1745-3674
DOI
10.3109/17453679108999247
language
English
LU publication?
yes
id
5abfdf33-1035-4255-9334-ab889c5ff138
date added to LUP
2016-05-04 18:20:01
date last changed
2024-01-04 02:47:15
@article{5abfdf33-1035-4255-9334-ab889c5ff138,
  abstract     = {{<p>Segments of the deep flexor tendon of the rabbit were exposed to air; the effects of dehydration on in vitro synthesis of proteoglycan, collagen, non-collagenous protein, and cell proliferation were compared with tendon segments that were kept moist with physiologic saline. After 20 min of expo-sure to air, the tendons lost half and after 40 min all of their ability to synthesize matrix components and to proliferate, whereas irrigated tendons remained viable during the entire experiment.</p>}},
  author       = {{Abrahamsson, Sven Olof and Lohmander, L. Stefan and Lundborg, Göran}},
  issn         = {{1745-3674}},
  language     = {{eng}},
  number       = {{2}},
  pages        = {{159--162}},
  publisher    = {{Taylor & Francis}},
  series       = {{Acta Orthopaedica}},
  title        = {{Dehydration inhibits matrix synthesis and cell proliferation : An in vitro study of rabbit flexor tendons}},
  url          = {{http://dx.doi.org/10.3109/17453679108999247}},
  doi          = {{10.3109/17453679108999247}},
  volume       = {{62}},
  year         = {{1991}},
}