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Reentrant condensation, liquid"liquid phase separation and crystallization in protein solutions induced by multivalent metal ions

Zhang, Fajun ; Roosen-Runge, Felix LU ; Sauter, Andrea ; Wolf, Marcell ; Jacobs, Robert M.J. and Schreiber, Frank (2014) In Pure and Applied Chemistry 86(2). p.191-202
Abstract

We briefly summarize the recent progress in tuning protein interactions as well as phase behavior in protein solutions using multivalent metal ions. We focus on the influence of control parameters and the mechanism of reentrant condensation, the metastable liquid"liquid phase separation and classical vs. nonclassical pathways of protein crystallization.

Please use this url to cite or link to this publication:
author
; ; ; ; and
publishing date
type
Contribution to journal
publication status
published
keywords
Charge inversion, Liquid"liquid phase separation, Multivalent salts, Protein crystallization, Protein interactions, Reentrant condensation, Zeta-potential
in
Pure and Applied Chemistry
volume
86
issue
2
pages
12 pages
publisher
IUPAC
external identifiers
  • scopus:84915818643
ISSN
0033-4545
DOI
10.1515/pac-2014-5002
language
English
LU publication?
no
id
5c04764e-ec9e-4b10-90e7-d0ab3626f6fa
date added to LUP
2018-12-17 09:47:50
date last changed
2022-04-25 19:51:09
@article{5c04764e-ec9e-4b10-90e7-d0ab3626f6fa,
  abstract     = {{<p>We briefly summarize the recent progress in tuning protein interactions as well as phase behavior in protein solutions using multivalent metal ions. We focus on the influence of control parameters and the mechanism of reentrant condensation, the metastable liquid"liquid phase separation and classical vs. nonclassical pathways of protein crystallization.</p>}},
  author       = {{Zhang, Fajun and Roosen-Runge, Felix and Sauter, Andrea and Wolf, Marcell and Jacobs, Robert M.J. and Schreiber, Frank}},
  issn         = {{0033-4545}},
  keywords     = {{Charge inversion; Liquid"liquid phase separation; Multivalent salts; Protein crystallization; Protein interactions; Reentrant condensation; Zeta-potential}},
  language     = {{eng}},
  month        = {{01}},
  number       = {{2}},
  pages        = {{191--202}},
  publisher    = {{IUPAC}},
  series       = {{Pure and Applied Chemistry}},
  title        = {{Reentrant condensation, liquid"liquid phase separation and crystallization in protein solutions induced by multivalent metal ions}},
  url          = {{http://dx.doi.org/10.1515/pac-2014-5002}},
  doi          = {{10.1515/pac-2014-5002}},
  volume       = {{86}},
  year         = {{2014}},
}