Cytogenetic abnormalities in a hemangiopericytoma of the spleen.
(2002) In Cancer Genetics and Cytogenetics 136(1). p.62-65- Abstract
- To date, only 16 cytogenetically abnormal hemangiopericytomas (HP) have been reported. Despite this low number, some characteristic karyotypic features have already emerged: most HP are near-diploid and breakpoints in 12q13, 12q24, and 19q13 seem to be common, with t(12;19)(q13;q13) being a recurrent translocation. Here, we report the first case of a probably benign splenic HP with chromosomal abnormalities. The abnormal karyotype was 47,XX,t(5;22;11)(q31;q11;q13),+10. None of these abnormalities have previously been reported in HP, suggesting that the karyotypic pattern of splenic HP may differ from soft tissue HP.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/109784
- author
- Hallén, Magnus LU ; Parada, Luis A ; Gorunova, Ludmila LU ; Pålsson, Birger LU ; Dictor, Michael LU and Johansson, Bertil LU
- organization
- publishing date
- 2002
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- Male, Karyotyping, Immunohistochemistry, Human, Hemangiopericytoma : genetics, Female, Cytogenetic Analysis, Case Report, Chromosome Aberrations, Splenic Neoplasms : genetics
- in
- Cancer Genetics and Cytogenetics
- volume
- 136
- issue
- 1
- pages
- 62 - 65
- publisher
- Elsevier
- external identifiers
-
- wos:000177326500011
- scopus:0036648444
- ISSN
- 0165-4608
- DOI
- 10.1016/S0165-4608(01)00664-1
- language
- English
- LU publication?
- yes
- additional info
- The information about affiliations in this record was updated in December 2015. The record was previously connected to the following departments: Surgery (Lund) (013009000), Division of Clinical Genetics (013022003), Pathology, (Lund) (013030000), Surgery Research Unit (013242220)
- id
- 5d352a1f-9507-4ad0-92ab-3efd16cea585 (old id 109784)
- alternative location
- http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=12165454&dopt=Abstract
- date added to LUP
- 2016-04-01 15:26:49
- date last changed
- 2022-01-28 05:21:42
@article{5d352a1f-9507-4ad0-92ab-3efd16cea585,
abstract = {{To date, only 16 cytogenetically abnormal hemangiopericytomas (HP) have been reported. Despite this low number, some characteristic karyotypic features have already emerged: most HP are near-diploid and breakpoints in 12q13, 12q24, and 19q13 seem to be common, with t(12;19)(q13;q13) being a recurrent translocation. Here, we report the first case of a probably benign splenic HP with chromosomal abnormalities. The abnormal karyotype was 47,XX,t(5;22;11)(q31;q11;q13),+10. None of these abnormalities have previously been reported in HP, suggesting that the karyotypic pattern of splenic HP may differ from soft tissue HP.}},
author = {{Hallén, Magnus and Parada, Luis A and Gorunova, Ludmila and Pålsson, Birger and Dictor, Michael and Johansson, Bertil}},
issn = {{0165-4608}},
keywords = {{Male; Karyotyping; Immunohistochemistry; Human; Hemangiopericytoma : genetics; Female; Cytogenetic Analysis; Case Report; Chromosome Aberrations; Splenic Neoplasms : genetics}},
language = {{eng}},
number = {{1}},
pages = {{62--65}},
publisher = {{Elsevier}},
series = {{Cancer Genetics and Cytogenetics}},
title = {{Cytogenetic abnormalities in a hemangiopericytoma of the spleen.}},
url = {{http://dx.doi.org/10.1016/S0165-4608(01)00664-1}},
doi = {{10.1016/S0165-4608(01)00664-1}},
volume = {{136}},
year = {{2002}},
}