Soft-MS and computational mapping of oleuropein
(2017) In International Journal of Molecular Sciences 18(5).- Abstract
Olive oil and table olives are rich sources of biophenols, which provides a unique taste, aroma and potential health benefits. Specifically, green olive drupes are enriched with oleuropein, a bioactive biophenol secoiridoid. Olive oil contains hydrolytic derivatives such as hydroxytyrosol, oleacein and elenolate from oleuropein as well as tyrosol and oleocanthal from ligstroside. Biophenol secoiridoids are categorized by the presence of elenoic acid or its derivatives in their molecular structure. Medical studies suggest that olive biophenol secoiridoids could prevent cancer, obesity, osteoporosis, and neurodegeneration. Therefore, understanding the biomolecular dynamics of oleuropein can potentially improve olive-based functional foods... (More)
Olive oil and table olives are rich sources of biophenols, which provides a unique taste, aroma and potential health benefits. Specifically, green olive drupes are enriched with oleuropein, a bioactive biophenol secoiridoid. Olive oil contains hydrolytic derivatives such as hydroxytyrosol, oleacein and elenolate from oleuropein as well as tyrosol and oleocanthal from ligstroside. Biophenol secoiridoids are categorized by the presence of elenoic acid or its derivatives in their molecular structure. Medical studies suggest that olive biophenol secoiridoids could prevent cancer, obesity, osteoporosis, and neurodegeneration. Therefore, understanding the biomolecular dynamics of oleuropein can potentially improve olive-based functional foods and nutraceuticals. This review provides a critical assessment of oleuropein biomolecular mechanism and computational mapping that could contribute to nutrigenomics.
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- author
- Gentile, Luigi LU ; Uccella, Nicola A. and Sivakumar, Ganapathy
- organization
- publishing date
- 2017-05-06
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- Biophenols, Hydroxytyrosol, Olive oil, Secoiridoid, Table olives, Tyrosol, β-glucosidase
- in
- International Journal of Molecular Sciences
- volume
- 18
- issue
- 5
- article number
- 992
- publisher
- MDPI AG
- external identifiers
-
- scopus:85019059233
- pmid:28481240
- wos:000404113900099
- ISSN
- 1661-6596
- DOI
- 10.3390/ijms18050992
- language
- English
- LU publication?
- yes
- id
- 5db91aab-61e7-4cf6-aa48-410b9f1b08d4
- date added to LUP
- 2017-05-31 08:57:58
- date last changed
- 2025-01-20 15:50:39
@article{5db91aab-61e7-4cf6-aa48-410b9f1b08d4, abstract = {{<p>Olive oil and table olives are rich sources of biophenols, which provides a unique taste, aroma and potential health benefits. Specifically, green olive drupes are enriched with oleuropein, a bioactive biophenol secoiridoid. Olive oil contains hydrolytic derivatives such as hydroxytyrosol, oleacein and elenolate from oleuropein as well as tyrosol and oleocanthal from ligstroside. Biophenol secoiridoids are categorized by the presence of elenoic acid or its derivatives in their molecular structure. Medical studies suggest that olive biophenol secoiridoids could prevent cancer, obesity, osteoporosis, and neurodegeneration. Therefore, understanding the biomolecular dynamics of oleuropein can potentially improve olive-based functional foods and nutraceuticals. This review provides a critical assessment of oleuropein biomolecular mechanism and computational mapping that could contribute to nutrigenomics.</p>}}, author = {{Gentile, Luigi and Uccella, Nicola A. and Sivakumar, Ganapathy}}, issn = {{1661-6596}}, keywords = {{Biophenols; Hydroxytyrosol; Olive oil; Secoiridoid; Table olives; Tyrosol; β-glucosidase}}, language = {{eng}}, month = {{05}}, number = {{5}}, publisher = {{MDPI AG}}, series = {{International Journal of Molecular Sciences}}, title = {{Soft-MS and computational mapping of oleuropein}}, url = {{http://dx.doi.org/10.3390/ijms18050992}}, doi = {{10.3390/ijms18050992}}, volume = {{18}}, year = {{2017}}, }