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Soft-MS and computational mapping of oleuropein

Gentile, Luigi LU ; Uccella, Nicola A. and Sivakumar, Ganapathy (2017) In International Journal of Molecular Sciences 18(5).
Abstract

Olive oil and table olives are rich sources of biophenols, which provides a unique taste, aroma and potential health benefits. Specifically, green olive drupes are enriched with oleuropein, a bioactive biophenol secoiridoid. Olive oil contains hydrolytic derivatives such as hydroxytyrosol, oleacein and elenolate from oleuropein as well as tyrosol and oleocanthal from ligstroside. Biophenol secoiridoids are categorized by the presence of elenoic acid or its derivatives in their molecular structure. Medical studies suggest that olive biophenol secoiridoids could prevent cancer, obesity, osteoporosis, and neurodegeneration. Therefore, understanding the biomolecular dynamics of oleuropein can potentially improve olive-based functional foods... (More)

Olive oil and table olives are rich sources of biophenols, which provides a unique taste, aroma and potential health benefits. Specifically, green olive drupes are enriched with oleuropein, a bioactive biophenol secoiridoid. Olive oil contains hydrolytic derivatives such as hydroxytyrosol, oleacein and elenolate from oleuropein as well as tyrosol and oleocanthal from ligstroside. Biophenol secoiridoids are categorized by the presence of elenoic acid or its derivatives in their molecular structure. Medical studies suggest that olive biophenol secoiridoids could prevent cancer, obesity, osteoporosis, and neurodegeneration. Therefore, understanding the biomolecular dynamics of oleuropein can potentially improve olive-based functional foods and nutraceuticals. This review provides a critical assessment of oleuropein biomolecular mechanism and computational mapping that could contribute to nutrigenomics.

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author
organization
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type
Contribution to journal
publication status
published
subject
keywords
Biophenols, Hydroxytyrosol, Olive oil, Secoiridoid, Table olives, Tyrosol, β-glucosidase
in
International Journal of Molecular Sciences
volume
18
issue
5
publisher
MOLECULAR DIVERSITY PRESERVATION INT
external identifiers
  • scopus:85019059233
  • wos:000404113900099
ISSN
1661-6596
DOI
10.3390/ijms18050992
language
English
LU publication?
yes
id
5db91aab-61e7-4cf6-aa48-410b9f1b08d4
date added to LUP
2017-05-31 08:57:58
date last changed
2017-09-18 11:38:15
@article{5db91aab-61e7-4cf6-aa48-410b9f1b08d4,
  abstract     = {<p>Olive oil and table olives are rich sources of biophenols, which provides a unique taste, aroma and potential health benefits. Specifically, green olive drupes are enriched with oleuropein, a bioactive biophenol secoiridoid. Olive oil contains hydrolytic derivatives such as hydroxytyrosol, oleacein and elenolate from oleuropein as well as tyrosol and oleocanthal from ligstroside. Biophenol secoiridoids are categorized by the presence of elenoic acid or its derivatives in their molecular structure. Medical studies suggest that olive biophenol secoiridoids could prevent cancer, obesity, osteoporosis, and neurodegeneration. Therefore, understanding the biomolecular dynamics of oleuropein can potentially improve olive-based functional foods and nutraceuticals. This review provides a critical assessment of oleuropein biomolecular mechanism and computational mapping that could contribute to nutrigenomics.</p>},
  articleno    = {992},
  author       = {Gentile, Luigi and Uccella, Nicola A. and Sivakumar, Ganapathy},
  issn         = {1661-6596},
  keyword      = {Biophenols,Hydroxytyrosol,Olive oil,Secoiridoid,Table olives,Tyrosol,β-glucosidase},
  language     = {eng},
  month        = {05},
  number       = {5},
  publisher    = {MOLECULAR DIVERSITY PRESERVATION INT},
  series       = {International Journal of Molecular Sciences},
  title        = {Soft-MS and computational mapping of oleuropein},
  url          = {http://dx.doi.org/10.3390/ijms18050992},
  volume       = {18},
  year         = {2017},
}