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Flow-injection immunoassays : Present and future

Pollema, Cy H. ; Ruzicka, Jaromir ; Lernmark, Åke LU orcid and Christian, Gary D. (1992) In Microchemical Journal 45(2). p.121-128
Abstract

The recent development of the flow-injection immunoassay (FIIA), beginning with one of the first publications in 1980 by Lim and Miller, has resulted in a growing field which combines the precise and reproducible timing of flow-injection analysis (FIA) with immunoassays to yield assays which are carried out in a nonequilibrium time frame. These often faster assay methods require small volumes of sample and reduced sample handling. The advancement of this field is briefly reviewed in this paper with respect to the general methods and detection schemes applied. A novel method utilizing sequential injection (SI) is also introduced. The method uses immunomagnetic beads to create a renewable reaction column which does not require in-line... (More)

The recent development of the flow-injection immunoassay (FIIA), beginning with one of the first publications in 1980 by Lim and Miller, has resulted in a growing field which combines the precise and reproducible timing of flow-injection analysis (FIA) with immunoassays to yield assays which are carried out in a nonequilibrium time frame. These often faster assay methods require small volumes of sample and reduced sample handling. The advancement of this field is briefly reviewed in this paper with respect to the general methods and detection schemes applied. A novel method utilizing sequential injection (SI) is also introduced. The method uses immunomagnetic beads to create a renewable reaction column which does not require in-line regeneration.

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author
; ; and
publishing date
type
Contribution to journal
publication status
published
subject
in
Microchemical Journal
volume
45
issue
2
pages
8 pages
publisher
Elsevier
external identifiers
  • scopus:0000007601
ISSN
0026-265X
DOI
10.1016/0026-265X(92)90003-L
language
English
LU publication?
no
id
5e882680-4692-4b8b-b2da-ab59cd976b50
date added to LUP
2019-09-11 09:34:48
date last changed
2021-01-03 11:21:22
@article{5e882680-4692-4b8b-b2da-ab59cd976b50,
  abstract     = {{<p>The recent development of the flow-injection immunoassay (FIIA), beginning with one of the first publications in 1980 by Lim and Miller, has resulted in a growing field which combines the precise and reproducible timing of flow-injection analysis (FIA) with immunoassays to yield assays which are carried out in a nonequilibrium time frame. These often faster assay methods require small volumes of sample and reduced sample handling. The advancement of this field is briefly reviewed in this paper with respect to the general methods and detection schemes applied. A novel method utilizing sequential injection (SI) is also introduced. The method uses immunomagnetic beads to create a renewable reaction column which does not require in-line regeneration.</p>}},
  author       = {{Pollema, Cy H. and Ruzicka, Jaromir and Lernmark, Åke and Christian, Gary D.}},
  issn         = {{0026-265X}},
  language     = {{eng}},
  month        = {{01}},
  number       = {{2}},
  pages        = {{121--128}},
  publisher    = {{Elsevier}},
  series       = {{Microchemical Journal}},
  title        = {{Flow-injection immunoassays : Present and future}},
  url          = {{http://dx.doi.org/10.1016/0026-265X(92)90003-L}},
  doi          = {{10.1016/0026-265X(92)90003-L}},
  volume       = {{45}},
  year         = {{1992}},
}