Nonlamellar lipid liquid crystalline model surfaces for biofunctional studies
(2013) In Soft Matter 9(37). p.8815-8819- Abstract
- Nonlamellar lipid liquid crystalline (LC) bulk phases and dispersions show promise as functional nanostructured materials for potential use as controlled release matrices e. g. in pharmaceuticals. Herein, methods for preparing and characterizing thin films of lipid liquid crystalline phases on solid surfaces are presented. The thickness, hydration phase structure and surface topography of spin-coated films of mixtures of soy phosphatidylcholine and glycerol dioleate are characterized by means of spectroscopic ellipsometry, small angle X-ray diffraction and atomic force microscopy. Besides being useful as bioadhesive drug delivery systems, the lipid nonlamellar LC films produced may also be exploited as model surfaces for studying... (More)
- Nonlamellar lipid liquid crystalline (LC) bulk phases and dispersions show promise as functional nanostructured materials for potential use as controlled release matrices e. g. in pharmaceuticals. Herein, methods for preparing and characterizing thin films of lipid liquid crystalline phases on solid surfaces are presented. The thickness, hydration phase structure and surface topography of spin-coated films of mixtures of soy phosphatidylcholine and glycerol dioleate are characterized by means of spectroscopic ellipsometry, small angle X-ray diffraction and atomic force microscopy. Besides being useful as bioadhesive drug delivery systems, the lipid nonlamellar LC films produced may also be exploited as model surfaces for studying properties such as bioadhesion and biodegradation. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/4062647
- author
- Wadsäter, Maria LU ; Barauskas, Justas ; Nylander, Tommy LU and Tiberg, Fredrik LU
- organization
- publishing date
- 2013
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Soft Matter
- volume
- 9
- issue
- 37
- pages
- 8815 - 8819
- publisher
- Royal Society of Chemistry
- external identifiers
-
- wos:000323844600003
- scopus:84883317929
- ISSN
- 1744-6848
- DOI
- 10.1039/c3sm51385h
- language
- English
- LU publication?
- yes
- id
- 5efdbb6d-2c4d-455c-8608-558308938d8f (old id 4062647)
- date added to LUP
- 2016-04-01 13:46:16
- date last changed
- 2023-09-03 04:53:57
@article{5efdbb6d-2c4d-455c-8608-558308938d8f,
abstract = {{Nonlamellar lipid liquid crystalline (LC) bulk phases and dispersions show promise as functional nanostructured materials for potential use as controlled release matrices e. g. in pharmaceuticals. Herein, methods for preparing and characterizing thin films of lipid liquid crystalline phases on solid surfaces are presented. The thickness, hydration phase structure and surface topography of spin-coated films of mixtures of soy phosphatidylcholine and glycerol dioleate are characterized by means of spectroscopic ellipsometry, small angle X-ray diffraction and atomic force microscopy. Besides being useful as bioadhesive drug delivery systems, the lipid nonlamellar LC films produced may also be exploited as model surfaces for studying properties such as bioadhesion and biodegradation.}},
author = {{Wadsäter, Maria and Barauskas, Justas and Nylander, Tommy and Tiberg, Fredrik}},
issn = {{1744-6848}},
language = {{eng}},
number = {{37}},
pages = {{8815--8819}},
publisher = {{Royal Society of Chemistry}},
series = {{Soft Matter}},
title = {{Nonlamellar lipid liquid crystalline model surfaces for biofunctional studies}},
url = {{http://dx.doi.org/10.1039/c3sm51385h}},
doi = {{10.1039/c3sm51385h}},
volume = {{9}},
year = {{2013}},
}