Acute plateletpheresis and aprotinin reduces the need for blood transfusion following Ross operation.
(2007) In Interactive Cardiovascular and Thoracic Surgery 6(5). p.618-622- Abstract
- The effect of acute intraoperative plateletpheresis (25% platelet yield) in combination with intraoperative low-dose aprotinin (2 million units) on blood conservation was investigated in 18 young adult patients undergoing elective Ross operation. The results were compared with a group of 19 similar patients without plateletpheresis (control group). The hematological and coagulation parameters at admission and discharge were statistically similar in both groups. The total blood product transfusion requirements were significantly reduced in the plateletpheresis group compared with the control group (3.2 units and 5.1 units, respectively, P=0.036). The total blood donor exposure was also reduced significantly in the plateletpheresis group... (More)
- The effect of acute intraoperative plateletpheresis (25% platelet yield) in combination with intraoperative low-dose aprotinin (2 million units) on blood conservation was investigated in 18 young adult patients undergoing elective Ross operation. The results were compared with a group of 19 similar patients without plateletpheresis (control group). The hematological and coagulation parameters at admission and discharge were statistically similar in both groups. The total blood product transfusion requirements were significantly reduced in the plateletpheresis group compared with the control group (3.2 units and 5.1 units, respectively, P=0.036). The total blood donor exposure was also reduced significantly in the plateletpheresis group compared with the control group (3.2 and 6.9 donors/patient, respectively, P<0.001). The direct costs for the hospital for the plateletpheresis procedure, including costs for all blood products, were similar to those for blood products alone in the control group. In summary, acute plateletpheresis in combination with low-dose aprotinin significantly reduces the blood product transfusions and blood donor exposures following the Ross operation; the treatment is cost-effective. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/607134
- author
- Al-Rashidi, Faleh ; Bhat, Misha LU ; Pierre, Leif LU and Koul, Bansi LU
- publishing date
- 2007-07-25
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Interactive Cardiovascular and Thoracic Surgery
- volume
- 6
- issue
- 5
- pages
- 618 - 622
- publisher
- European Association of Cardio-Thoracic Surgery
- external identifiers
-
- scopus:34848922384
- ISSN
- 1569-9285
- language
- English
- LU publication?
- no
- id
- b4bcfe3e-e9bd-41d6-bd0a-32b825fae753 (old id 607134)
- alternative location
- http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17670731&dopt=Abstract
- date added to LUP
- 2016-04-04 08:56:32
- date last changed
- 2022-02-28 06:05:27
@article{b4bcfe3e-e9bd-41d6-bd0a-32b825fae753, abstract = {{The effect of acute intraoperative plateletpheresis (25% platelet yield) in combination with intraoperative low-dose aprotinin (2 million units) on blood conservation was investigated in 18 young adult patients undergoing elective Ross operation. The results were compared with a group of 19 similar patients without plateletpheresis (control group). The hematological and coagulation parameters at admission and discharge were statistically similar in both groups. The total blood product transfusion requirements were significantly reduced in the plateletpheresis group compared with the control group (3.2 units and 5.1 units, respectively, P=0.036). The total blood donor exposure was also reduced significantly in the plateletpheresis group compared with the control group (3.2 and 6.9 donors/patient, respectively, P<0.001). The direct costs for the hospital for the plateletpheresis procedure, including costs for all blood products, were similar to those for blood products alone in the control group. In summary, acute plateletpheresis in combination with low-dose aprotinin significantly reduces the blood product transfusions and blood donor exposures following the Ross operation; the treatment is cost-effective.}}, author = {{Al-Rashidi, Faleh and Bhat, Misha and Pierre, Leif and Koul, Bansi}}, issn = {{1569-9285}}, language = {{eng}}, month = {{07}}, number = {{5}}, pages = {{618--622}}, publisher = {{European Association of Cardio-Thoracic Surgery}}, series = {{Interactive Cardiovascular and Thoracic Surgery}}, title = {{Acute plateletpheresis and aprotinin reduces the need for blood transfusion following Ross operation.}}, url = {{http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17670731&dopt=Abstract}}, volume = {{6}}, year = {{2007}}, }