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Measurements of optical properties of pig brain tissue in vitro using a novel compact device

Yavari, Nazila LU ; Dam, Jan Sorensen ; Antonsson, Johan ; Wardell, Karin and Andersson-Engels, Stefan LU (2005) Novel Optical Instrumentation for Biomedical Applications II 5864. p.1-11
Abstract
In numerous medical and scientific fields, knowledge of the optical properties of tissues can be applied. Among many different ways of determining the optical properties of turbid media; integrating sphere measurements are widely used. However, this technique is associated with bulky equipment, complicated measuring techniques, interference compensation techniques, and inconvenient sample handling. This paper describes measurements of the optical properties of porcine brain tissue using novel instrumentation for simultaneous absorption and scattering characterization of small turbid samples. The system used measures both angularly and spatially resolved transmission and reflection and is called Combined Angular and Spatially-resolved Head... (More)
In numerous medical and scientific fields, knowledge of the optical properties of tissues can be applied. Among many different ways of determining the optical properties of turbid media; integrating sphere measurements are widely used. However, this technique is associated with bulky equipment, complicated measuring techniques, interference compensation techniques, and inconvenient sample handling. This paper describes measurements of the optical properties of porcine brain tissue using novel instrumentation for simultaneous absorption and scattering characterization of small turbid samples. The system used measures both angularly and spatially resolved transmission and reflection and is called Combined Angular and Spatially-resolved Head (CASH) sensor. The results compare very well with data obtained with an integrating sphere for well-defined samples. The instrument was shown to be accurate to within 12 % for μ<sub>a</sub>. and 1 % for μ<sub>s</sub>' in measurements of intralipid-ink samples. The corresponding variations of data were 17 %, and 2 %, respectively. The reduced scattering coefficient for porcine white matter was measured to be 100 cm<sup>-1</sup>, while the value for coagulated brain tissue was 65 cm<sup>-1</sup>. The corresponding absorption coefficients were 2 and 3 cm<sup>-1</sup>, respectively. © 2005 SPIE and OSA. (Less)
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author
; ; ; and
organization
publishing date
type
Chapter in Book/Report/Conference proceeding
publication status
published
subject
keywords
Absorption coefficients, Pig brain tissue, Turbid media, Optical device
host publication
Progress in Biomedical Optics and Imaging - Proceedings of SPIE
volume
5864
pages
1 - 11
publisher
International Society for Optical Engineering
conference name
Novel Optical Instrumentation for Biomedical Applications II
conference location
Munich, Germany
conference dates
2005-06-12 - 2005-06-16
external identifiers
  • scopus:28844462086
ISSN
1605-7422
1042-4687
DOI
10.1117/12.632926
language
English
LU publication?
yes
id
989b4f8d-cc65-41d0-8584-06afa5a8627d (old id 615937)
date added to LUP
2016-04-01 12:08:13
date last changed
2021-02-17 06:37:20
@inproceedings{989b4f8d-cc65-41d0-8584-06afa5a8627d,
  abstract     = {In numerous medical and scientific fields, knowledge of the optical properties of tissues can be applied. Among many different ways of determining the optical properties of turbid media; integrating sphere measurements are widely used. However, this technique is associated with bulky equipment, complicated measuring techniques, interference compensation techniques, and inconvenient sample handling. This paper describes measurements of the optical properties of porcine brain tissue using novel instrumentation for simultaneous absorption and scattering characterization of small turbid samples. The system used measures both angularly and spatially resolved transmission and reflection and is called Combined Angular and Spatially-resolved Head (CASH) sensor. The results compare very well with data obtained with an integrating sphere for well-defined samples. The instrument was shown to be accurate to within 12 % for μ&lt;sub&gt;a&lt;/sub&gt;. and 1 % for μ&lt;sub&gt;s&lt;/sub&gt;' in measurements of intralipid-ink samples. The corresponding variations of data were 17 %, and 2 %, respectively. The reduced scattering coefficient for porcine white matter was measured to be 100 cm&lt;sup&gt;-1&lt;/sup&gt;, while the value for coagulated brain tissue was 65 cm&lt;sup&gt;-1&lt;/sup&gt;. The corresponding absorption coefficients were 2 and 3 cm&lt;sup&gt;-1&lt;/sup&gt;, respectively. © 2005 SPIE and OSA.},
  author       = {Yavari, Nazila and Dam, Jan Sorensen and Antonsson, Johan and Wardell, Karin and Andersson-Engels, Stefan},
  booktitle    = {Progress in Biomedical Optics and Imaging - Proceedings of SPIE},
  issn         = {1605-7422},
  language     = {eng},
  pages        = {1--11},
  publisher    = {International Society for Optical Engineering},
  title        = {Measurements of optical properties of pig brain tissue in vitro using a novel compact device},
  url          = {http://dx.doi.org/10.1117/12.632926},
  doi          = {10.1117/12.632926},
  volume       = {5864},
  year         = {2005},
}