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Cardiovascular Magnetic Resonance for Patients With COVID-19

Petersen, Steffen E ; Friedrich, Matthias G ; Leiner, Tim ; Elias, Matthew D ; Ferreira, Vanessa M ; Fenski, Maximilian ; Flamm, Scott D ; Fogel, Mark ; Garg, Ria and Halushka, Marc K , et al. (2022) In JACC: Cardiovascular Imaging 15(4). p.685-699
Abstract

COVID-19 is associated with myocardial injury caused by ischemia, inflammation, or myocarditis. Cardiovascular magnetic resonance (CMR) is the noninvasive reference standard for cardiac function, structure, and tissue composition. CMR is a potentially valuable diagnostic tool in patients with COVID-19 presenting with myocardial injury and evidence of cardiac dysfunction. Although COVID-19-related myocarditis is likely infrequent, COVID-19-related cardiovascular histopathology findings have been reported in up to 48% of patients, raising the concern for long-term myocardial injury. Studies to date report CMR abnormalities in 26% to 60% of hospitalized patients who have recovered from COVID-19, including functional impairment, myocardial... (More)

COVID-19 is associated with myocardial injury caused by ischemia, inflammation, or myocarditis. Cardiovascular magnetic resonance (CMR) is the noninvasive reference standard for cardiac function, structure, and tissue composition. CMR is a potentially valuable diagnostic tool in patients with COVID-19 presenting with myocardial injury and evidence of cardiac dysfunction. Although COVID-19-related myocarditis is likely infrequent, COVID-19-related cardiovascular histopathology findings have been reported in up to 48% of patients, raising the concern for long-term myocardial injury. Studies to date report CMR abnormalities in 26% to 60% of hospitalized patients who have recovered from COVID-19, including functional impairment, myocardial tissue abnormalities, late gadolinium enhancement, or pericardial abnormalities. In athletes post-COVID-19, CMR has detected myocarditis-like abnormalities. In children, multisystem inflammatory syndrome may occur 2 to 6 weeks after infection; associated myocarditis and coronary artery aneurysms are evaluable by CMR. At this time, our understanding of COVID-19-related cardiovascular involvement is incomplete, and multiple studies are planned to evaluate patients with COVID-19 using CMR. In this review, we summarize existing studies of CMR for patients with COVID-19 and present ongoing research. We also provide recommendations for clinical use of CMR for patients with acute symptoms or who are recovering from COVID-19.

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organization
publishing date
type
Contribution to journal
publication status
published
subject
in
JACC: Cardiovascular Imaging
volume
15
issue
4
pages
685 - 699
publisher
Elsevier
external identifiers
  • pmid:34656482
  • scopus:85123513653
ISSN
1876-7591
DOI
10.1016/j.jcmg.2021.08.021
language
English
LU publication?
yes
additional info
Crown Copyright © 2021. Published by Elsevier Inc. All rights reserved.
id
61a70d9b-111d-4eb8-be25-99c31da41aac
date added to LUP
2022-03-16 11:07:59
date last changed
2024-12-14 07:48:00
@article{61a70d9b-111d-4eb8-be25-99c31da41aac,
  abstract     = {{<p>COVID-19 is associated with myocardial injury caused by ischemia, inflammation, or myocarditis. Cardiovascular magnetic resonance (CMR) is the noninvasive reference standard for cardiac function, structure, and tissue composition. CMR is a potentially valuable diagnostic tool in patients with COVID-19 presenting with myocardial injury and evidence of cardiac dysfunction. Although COVID-19-related myocarditis is likely infrequent, COVID-19-related cardiovascular histopathology findings have been reported in up to 48% of patients, raising the concern for long-term myocardial injury. Studies to date report CMR abnormalities in 26% to 60% of hospitalized patients who have recovered from COVID-19, including functional impairment, myocardial tissue abnormalities, late gadolinium enhancement, or pericardial abnormalities. In athletes post-COVID-19, CMR has detected myocarditis-like abnormalities. In children, multisystem inflammatory syndrome may occur 2 to 6 weeks after infection; associated myocarditis and coronary artery aneurysms are evaluable by CMR. At this time, our understanding of COVID-19-related cardiovascular involvement is incomplete, and multiple studies are planned to evaluate patients with COVID-19 using CMR. In this review, we summarize existing studies of CMR for patients with COVID-19 and present ongoing research. We also provide recommendations for clinical use of CMR for patients with acute symptoms or who are recovering from COVID-19.</p>}},
  author       = {{Petersen, Steffen E and Friedrich, Matthias G and Leiner, Tim and Elias, Matthew D and Ferreira, Vanessa M and Fenski, Maximilian and Flamm, Scott D and Fogel, Mark and Garg, Ria and Halushka, Marc K and Hays, Allison G and Kawel-Boehm, Nadine and Kramer, Christopher M and Nagel, Eike and Ntusi, Ntobeko A B and Ostenfeld, Ellen and Pennell, Dudley J and Raisi-Estabragh, Zahra and Reeder, Scott B and Rochitte, Carlos E and Starekova, Jitka and Suchá, Dominika and Tao, Qian and Schulz-Menger, Jeanette and Bluemke, David A}},
  issn         = {{1876-7591}},
  language     = {{eng}},
  number       = {{4}},
  pages        = {{685--699}},
  publisher    = {{Elsevier}},
  series       = {{JACC: Cardiovascular Imaging}},
  title        = {{Cardiovascular Magnetic Resonance for Patients With COVID-19}},
  url          = {{http://dx.doi.org/10.1016/j.jcmg.2021.08.021}},
  doi          = {{10.1016/j.jcmg.2021.08.021}},
  volume       = {{15}},
  year         = {{2022}},
}