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Extreme intracranial pressure elevation > 90 mmHg in an awake patient with primary CNS lymphoma—case report

Cederberg, David LU ; Marklund, Niklas LU orcid and Nittby Redebrandt, Henrietta LU (2020) In Acta Neurochirurgica 162(8). p.1819-1823
Abstract

We describe a patient with primary CNS lymphomas, awake despite an extreme ICP elevation. A 48-year-old woman presented with headache since 1 month, and bilateral papillary edema was observed. Magnetic resonance imaging revealed diffuse infiltration around the petrous bone. Following external ventricular drainage (EVD) placement, ICP levels of > 90 mmHg were recorded while the patient was fully awake. Cytology revealed an aggressive primary CNS lymphoma. Cerebrospinal fluid (CSF) drainage at high opening pressure levels was required. We conclude that extreme ICP elevations, treatable by CSF drainage, can be observed without a reduced level of consciousness.

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author
; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Intracranial hypertension, Intracranial pressure, Lymphoma
in
Acta Neurochirurgica
volume
162
issue
8
pages
5 pages
publisher
Springer
external identifiers
  • scopus:85078314404
  • pmid:31965320
ISSN
0001-6268
DOI
10.1007/s00701-020-04231-x
language
English
LU publication?
yes
id
62a64925-e7a0-403b-8732-6611fcfcde5c
date added to LUP
2020-02-10 09:51:03
date last changed
2024-04-17 05:00:51
@article{62a64925-e7a0-403b-8732-6611fcfcde5c,
  abstract     = {{<p>We describe a patient with primary CNS lymphomas, awake despite an extreme ICP elevation. A 48-year-old woman presented with headache since 1 month, and bilateral papillary edema was observed. Magnetic resonance imaging revealed diffuse infiltration around the petrous bone. Following external ventricular drainage (EVD) placement, ICP levels of &gt; 90 mmHg were recorded while the patient was fully awake. Cytology revealed an aggressive primary CNS lymphoma. Cerebrospinal fluid (CSF) drainage at high opening pressure levels was required. We conclude that extreme ICP elevations, treatable by CSF drainage, can be observed without a reduced level of consciousness.</p>}},
  author       = {{Cederberg, David and Marklund, Niklas and Nittby Redebrandt, Henrietta}},
  issn         = {{0001-6268}},
  keywords     = {{Intracranial hypertension; Intracranial pressure; Lymphoma}},
  language     = {{eng}},
  number       = {{8}},
  pages        = {{1819--1823}},
  publisher    = {{Springer}},
  series       = {{Acta Neurochirurgica}},
  title        = {{Extreme intracranial pressure elevation > 90 mmHg in an awake patient with primary CNS lymphoma—case report}},
  url          = {{http://dx.doi.org/10.1007/s00701-020-04231-x}},
  doi          = {{10.1007/s00701-020-04231-x}},
  volume       = {{162}},
  year         = {{2020}},
}