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Tunable separation and DNA manipulation in metal coated pillar arrays

Beech, Jason P. LU ; Keim, Kevin ; Ho, Bao Dang LU ; Ström, Oskar LU orcid ; Guiducci, Carlotta and Tegenfeldt, Jonas O. LU orcid (2018) 22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2018 In 22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2018 4. p.2090-2093
Abstract

Implementing electrically connected metal-coated posts in a Deterministic Lateral Displacement (DLD) device and applying electric fields, we use electrokinetics to achieve tunable particle separations and to trap and manipulate DNA. The strength of DLD stems from its typically binary behavior. Particles move in one out of two trajectories based on their effective size. For particles that are close to the threshold size, a minute external force is sufficient to nudge the particles from one trajectory to another. Dielectrophoresis (DEP) provides such a force and also gives specificity based on the dielectric properties of the particles.

Please use this url to cite or link to this publication:
author
; ; ; ; and
organization
publishing date
type
Chapter in Book/Report/Conference proceeding
publication status
published
subject
keywords
Deterministic lateral displacement, Dielectrophoresis, Integrated electrodes, Particle separation
host publication
22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2018
series title
22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2018
volume
4
pages
4 pages
publisher
Chemical and Biological Microsystems Society
conference name
22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2018
conference location
Kaohsiung, Taiwan
conference dates
2018-11-11 - 2018-11-15
ISBN
9781510897571
language
English
LU publication?
yes
id
62d733e9-4520-4af2-b451-c45ea2367e9c
date added to LUP
2020-03-13 15:33:26
date last changed
2022-04-06 12:41:53
@inproceedings{62d733e9-4520-4af2-b451-c45ea2367e9c,
  abstract     = {{<p>Implementing electrically connected metal-coated posts in a Deterministic Lateral Displacement (DLD) device and applying electric fields, we use electrokinetics to achieve tunable particle separations and to trap and manipulate DNA. The strength of DLD stems from its typically binary behavior. Particles move in one out of two trajectories based on their effective size. For particles that are close to the threshold size, a minute external force is sufficient to nudge the particles from one trajectory to another. Dielectrophoresis (DEP) provides such a force and also gives specificity based on the dielectric properties of the particles.</p>}},
  author       = {{Beech, Jason P. and Keim, Kevin and Ho, Bao Dang and Ström, Oskar and Guiducci, Carlotta and Tegenfeldt, Jonas O.}},
  booktitle    = {{22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2018}},
  isbn         = {{9781510897571}},
  keywords     = {{Deterministic lateral displacement; Dielectrophoresis; Integrated electrodes; Particle separation}},
  language     = {{eng}},
  pages        = {{2090--2093}},
  publisher    = {{Chemical and Biological Microsystems Society}},
  series       = {{22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2018}},
  title        = {{Tunable separation and DNA manipulation in metal coated pillar arrays}},
  volume       = {{4}},
  year         = {{2018}},
}