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Familial malignant blood disease in the county of Jämtland, Sweden

Eriksson, Mikael LU orcid and Bergström, Ingmar (1987) In European Journal of Haematology 38(3). p.241-245
Abstract

In a material of 942 patients with malignant hematological disease, encompassing all diagnosed cases in the county of Jämtland in Sweden during a 22‐yr period, 36 families with multiple cases of such disease were found. Approximately 5% of the patients have at least one close relative who also suffers from a malignant hematological disease. An especially strong familial occurrence was found in the group of chronic lymphoproliferative diseases and it is concluded that this tendency comprises all diseases in the group, i.e. chronic lymphocytic leukemia, multiple myeloma and malignant lymphoma. In some families several cases of acute leukemia were present, and suggestions concerning immunological disturbances are made. In the group of... (More)

In a material of 942 patients with malignant hematological disease, encompassing all diagnosed cases in the county of Jämtland in Sweden during a 22‐yr period, 36 families with multiple cases of such disease were found. Approximately 5% of the patients have at least one close relative who also suffers from a malignant hematological disease. An especially strong familial occurrence was found in the group of chronic lymphoproliferative diseases and it is concluded that this tendency comprises all diseases in the group, i.e. chronic lymphocytic leukemia, multiple myeloma and malignant lymphoma. In some families several cases of acute leukemia were present, and suggestions concerning immunological disturbances are made. In the group of chronic myeloproliferative diseases familial factors do not seem to play an important. part, with the possible exception of polycythemia vera. Both heredity and common environmental agents must be considered as possible etiologic factors.

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author
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publishing date
type
Contribution to journal
publication status
published
subject
keywords
familial occurrence, heredity, leukemia, malignant lymphoma, multiple myeloma, polycythemia Vera
in
European Journal of Haematology
volume
38
issue
3
pages
241 - 245
publisher
Wiley-Blackwell
external identifiers
  • scopus:0023300922
  • pmid:3595812
ISSN
0902-4441
DOI
10.1111/j.1600-0609.1987.tb01170.x
language
English
LU publication?
no
id
63edb2c9-4f57-4ff8-8717-07685cdb4757
date added to LUP
2020-03-26 16:14:00
date last changed
2024-01-02 07:46:13
@article{63edb2c9-4f57-4ff8-8717-07685cdb4757,
  abstract     = {{<p>In a material of 942 patients with malignant hematological disease, encompassing all diagnosed cases in the county of Jämtland in Sweden during a 22‐yr period, 36 families with multiple cases of such disease were found. Approximately 5% of the patients have at least one close relative who also suffers from a malignant hematological disease. An especially strong familial occurrence was found in the group of chronic lymphoproliferative diseases and it is concluded that this tendency comprises all diseases in the group, i.e. chronic lymphocytic leukemia, multiple myeloma and malignant lymphoma. In some families several cases of acute leukemia were present, and suggestions concerning immunological disturbances are made. In the group of chronic myeloproliferative diseases familial factors do not seem to play an important. part, with the possible exception of polycythemia vera. Both heredity and common environmental agents must be considered as possible etiologic factors.</p>}},
  author       = {{Eriksson, Mikael and Bergström, Ingmar}},
  issn         = {{0902-4441}},
  keywords     = {{familial occurrence; heredity; leukemia; malignant lymphoma; multiple myeloma; polycythemia Vera}},
  language     = {{eng}},
  month        = {{01}},
  number       = {{3}},
  pages        = {{241--245}},
  publisher    = {{Wiley-Blackwell}},
  series       = {{European Journal of Haematology}},
  title        = {{Familial malignant blood disease in the county of Jämtland, Sweden}},
  url          = {{http://dx.doi.org/10.1111/j.1600-0609.1987.tb01170.x}},
  doi          = {{10.1111/j.1600-0609.1987.tb01170.x}},
  volume       = {{38}},
  year         = {{1987}},
}