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Effect of feed supplementation with alpha-ketoglutarate, combined with vitamin B-6 or C, on the performance and haemoglobin and amino acid levels in growing rats

Pierzynowski, Stefan LU ; Filip, Rafal and Harrison, Adrian (2007) In Bulletin of the Veterinary Institute in Puławy 51(2). p.289-296
Abstract
The aim of the study was to evaluate the influence of a-ketoglutarate (AKG), at pH 2 or 5, combined with vitamin B-6 (AKG 2B, AKG 5B) or C (AKG 2C, AKG 5C), on the performance and haemoglobin and amino acid levels in growing rats. Eighty rats were divided into 5 treatment groups and stayed on trial for 9 d (n=16) or 18 d (n=10). No significant differences in average daily gain (ADG), average daily feed intake (ADFI), or feed efficiency were seen between the dextrose-treated control group and the AKG treated groups. The highest ADG and ADFI were seen in the AKG 2B rats. The AKG 2B and AKG 2C treated rats had the highest Hb levels. The Hb levels were positively correlated with a better performance. The free glutamine (Glu) increased over... (More)
The aim of the study was to evaluate the influence of a-ketoglutarate (AKG), at pH 2 or 5, combined with vitamin B-6 (AKG 2B, AKG 5B) or C (AKG 2C, AKG 5C), on the performance and haemoglobin and amino acid levels in growing rats. Eighty rats were divided into 5 treatment groups and stayed on trial for 9 d (n=16) or 18 d (n=10). No significant differences in average daily gain (ADG), average daily feed intake (ADFI), or feed efficiency were seen between the dextrose-treated control group and the AKG treated groups. The highest ADG and ADFI were seen in the AKG 2B rats. The AKG 2B and AKG 2C treated rats had the highest Hb levels. The Hb levels were positively correlated with a better performance. The free glutamine (Glu) increased over time in all the groups. The arginine (Arg) levels significantly increased in the AKG 2B and AKG 5B groups. An increase in free Glu had a positive impact on the growth performance. (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
ascorbic acid, vitamin B6, rats, alpha-ketoglutaric acid, amino acids
in
Bulletin of the Veterinary Institute in Puławy
volume
51
issue
2
pages
289 - 296
publisher
National Veterinary Research Institute
external identifiers
  • wos:000247794900021
ISSN
0042-4870
language
English
LU publication?
yes
id
51d27611-9ecf-41e5-8a61-d03c6a4dafa4 (old id 645917)
date added to LUP
2007-12-18 17:13:41
date last changed
2016-04-16 02:58:43
@article{51d27611-9ecf-41e5-8a61-d03c6a4dafa4,
  abstract     = {The aim of the study was to evaluate the influence of a-ketoglutarate (AKG), at pH 2 or 5, combined with vitamin B-6 (AKG 2B, AKG 5B) or C (AKG 2C, AKG 5C), on the performance and haemoglobin and amino acid levels in growing rats. Eighty rats were divided into 5 treatment groups and stayed on trial for 9 d (n=16) or 18 d (n=10). No significant differences in average daily gain (ADG), average daily feed intake (ADFI), or feed efficiency were seen between the dextrose-treated control group and the AKG treated groups. The highest ADG and ADFI were seen in the AKG 2B rats. The AKG 2B and AKG 2C treated rats had the highest Hb levels. The Hb levels were positively correlated with a better performance. The free glutamine (Glu) increased over time in all the groups. The arginine (Arg) levels significantly increased in the AKG 2B and AKG 5B groups. An increase in free Glu had a positive impact on the growth performance.},
  author       = {Pierzynowski, Stefan and Filip, Rafal and Harrison, Adrian},
  issn         = {0042-4870},
  keyword      = {ascorbic acid,vitamin B6,rats,alpha-ketoglutaric acid,amino acids},
  language     = {eng},
  number       = {2},
  pages        = {289--296},
  publisher    = {National Veterinary Research Institute},
  series       = {Bulletin of the Veterinary Institute in Puławy},
  title        = {Effect of feed supplementation with alpha-ketoglutarate, combined with vitamin B-6 or C, on the performance and haemoglobin and amino acid levels in growing rats},
  volume       = {51},
  year         = {2007},
}