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Incomplete lipid chain freezing of sonicated vesicular dispersions of double-tailed ionic surfactants

Saveyn, Pieter LU ; Van der Meeren, Paul; Cocquyt, Jan; Drakenberg, Torbjörn LU ; Olofsson, Gerd LU and Olsson, Ulf LU (2007) In Langmuir 23(21). p.10455-10462
Abstract
Lipid freezing in dilute sonicated vesicular dispersions was studied using differential scanning calorimetry (DSC) and H-1 NMR. For charged, anionic, or cationic lipids, approximately half of the lipids remain in a fluid state when cooled 20 degrees C below the main chain melting temperature. With a zwitterionic phospholipid, on the other hand, essentially no supercooling of the liquid state was observed. The observations are analyzed in terms of the nucleation and growth of flat solid domains in originally fluid spherical vesicles. As the solid domains grow, the remaining fluid domain is deformed, resulting in a curvature stress. Depending on the vesicle size and the bilayer bending rigidity, the solid domain growth may terminate as the... (More)
Lipid freezing in dilute sonicated vesicular dispersions was studied using differential scanning calorimetry (DSC) and H-1 NMR. For charged, anionic, or cationic lipids, approximately half of the lipids remain in a fluid state when cooled 20 degrees C below the main chain melting temperature. With a zwitterionic phospholipid, on the other hand, essentially no supercooling of the liquid state was observed. The observations are analyzed in terms of the nucleation and growth of flat solid domains in originally fluid spherical vesicles. As the solid domains grow, the remaining fluid domain is deformed, resulting in a curvature stress. Depending on the vesicle size and the bilayer bending rigidity, the solid domain growth may terminate as the gain in cohesive free energy is balanced by the curvature stress of the remaining fluid domain. It is argued that high bending rigidities are required for, having a significant supercooling, which is why it is only observed for charged lipids. (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Langmuir
volume
23
issue
21
pages
10455 - 10462
publisher
The American Chemical Society
external identifiers
  • wos:000249948700007
  • scopus:35448992023
ISSN
0743-7463
DOI
10.1021/la701554d
language
English
LU publication?
yes
id
cbf0cb9a-6da2-4073-bad1-ce8f8597eb50 (old id 655166)
date added to LUP
2007-12-14 14:11:58
date last changed
2017-11-05 03:33:08
@article{cbf0cb9a-6da2-4073-bad1-ce8f8597eb50,
  abstract     = {Lipid freezing in dilute sonicated vesicular dispersions was studied using differential scanning calorimetry (DSC) and H-1 NMR. For charged, anionic, or cationic lipids, approximately half of the lipids remain in a fluid state when cooled 20 degrees C below the main chain melting temperature. With a zwitterionic phospholipid, on the other hand, essentially no supercooling of the liquid state was observed. The observations are analyzed in terms of the nucleation and growth of flat solid domains in originally fluid spherical vesicles. As the solid domains grow, the remaining fluid domain is deformed, resulting in a curvature stress. Depending on the vesicle size and the bilayer bending rigidity, the solid domain growth may terminate as the gain in cohesive free energy is balanced by the curvature stress of the remaining fluid domain. It is argued that high bending rigidities are required for, having a significant supercooling, which is why it is only observed for charged lipids.},
  author       = {Saveyn, Pieter and Van der Meeren, Paul and Cocquyt, Jan and Drakenberg, Torbjörn and Olofsson, Gerd and Olsson, Ulf},
  issn         = {0743-7463},
  language     = {eng},
  number       = {21},
  pages        = {10455--10462},
  publisher    = {The American Chemical Society},
  series       = {Langmuir},
  title        = {Incomplete lipid chain freezing of sonicated vesicular dispersions of double-tailed ionic surfactants},
  url          = {http://dx.doi.org/10.1021/la701554d},
  volume       = {23},
  year         = {2007},
}